doi:10.1093/fampra/cmi093 Family Practice Advance Access published on 14 November 2005 Pathways to the diagnosis of colorectal cancer: an observational study in three UK cities

observational study in three UK cities. Family Practice 2006; 23: 15–19. Background. Colorectal cancer can present in a variety of ways, and with any of several symptoms. Different referral routes from primary to secondary care cater for these different presentations. The route that has received most investment in the UK National Health Service is the 2-week clinic, but the proportions of patients taking this and other routes to diagnosis are largely unknown. Methods.We designed an observational audit in Exeter, Oxford and Sheffield, UK. Colorectal cancers diagnosed in 2002 from participating practices were identified and the presence and timing of seven important clinical features noted: diarrhoea, constipation, rectal bleeding, abdominal pain, the finding of an abdominal or rectal mass on examination, anaemia and positive faecal occult blood tests. The referral pathways to secondary care were identified. Results.Of the 151 patients studied, 112 (74%) were referred with at least one clinical feature of colorectal cancer to a specialist. Only 43 of these (28 % of the total) were referred to a 2-week clinic; 39 patients (26 % of the total) had an emergency admission, of whom 10 (7%) had their emergency admission after referral to a specialist for investigation but before a diagnosis had been established. The time intervals between the first consultation with a symptom of cancer and referral were mostly short. Conclusion. Patients with colorectal cancer travel several different pathways to diagnosis. The pathway with the most resources—the 2-week clinic—is used by a minority of patients