ORIGINAL ARTICLE ROLE OF ENDOSCOPIC SURGERY IN THE MANAGEMENT OF SELECTED MALIGNANT EPITHELIAL NEOPLASMS OF THE

Abstract: Background. This study reviews the outcome of patients with adenocarcinoma (AC) and squamous cell carci-noma (SCC) of the naso-ethmoidal complex treated by endo-scopic surgery. Methods. Sixteen patients underwent a purely endoscopic excision of AC (n 12) or SCC (n 4) at 2 university hospitals. All patients were prospectively followed by endoscopic and MRI evaluations. Results. The tumor originated from the ethmoid in 13 cases and the nasal fossa in 3. Lesions were staged as follows: 5 T1, 10 T2, and 1 T3. Adjuvant radiotherapy was delivered in 7 cases. Follow-up (range, 28–70 months; mean, 47.25) was available for all patients. One patient died for brain metastases 28 months after surgery. Another patient required salvage craniofacial resection and radiotherapy for recurrent AC. Five-year disease-specific and disease-free survival rates were 93.3 % and 87.0%, respectively. Conclusions. In selected T1-T2 lesions of the naso-ethmoidal complex, endoscopic surgery seems to offer a satisfactory alter-native to external procedures. VC 2007 Wiley Periodicals, Inc