EDITORIAL Monitoring of pulmonary function in Pompe disease: a

muscle disease with new therapeutic perspectives A.T. van der Ploeg M onitoring of pulmonary function and timely initiation of noninvasive ventilation should be a focus in supportive care for patients with muscular disorders. In the current issue of the European Respiratory Journal, PELLEGRINI et al. [1] focus on this aspect in patients with late-onset Pompe disease (glycogenosis type II, acid maltase deficiency) [1]. In Pompe disease, correct monitoring of pulmonary function and initiation of supportive care is even more relevant since new therapeutic developments are under-way. The first reports on the effects of enzyme therapy for this disease are promising [2–4]. Pompe disease is an autosomal, recessive, metabolic myopath