In teleosts, the Yolk Syncytial Layer (YSL) is functionally similar to the anterior visceral endoderm found in mice and is required for morphogenesis of the overlying blastoderm. The YSL undergoes dramatic reorganization during early development through processes that mirror the morphogenetic movements of the blastoderm. The YSL and YSL nuclei (YSN) undergo epiboly, and during convergence and extension movements of the blastoderm, the YSN underneath the animal cap also converge and extend underneath the axial hypoblast. Our work with pollywog ( pwg ) maternal-effect mutants highlights the delicate control of the YSL during yolk morphogenesis, and provides novel insight into understanding which tissues of the embryo are affected by loss of a...
AbstractRecent studies in mouse suggest that the extraembryonic endoderm has an important role in ea...
SummaryIn vertebrates, extraembryonic tissues can act as signaling centers that impose a reproducibl...
AbstractEpiboly, the first morphogenetic cell movement that occurs in the zebrafish embryo, is the p...
One of the earliest morphogenetic processes in the development of many animals is epiboly. In the ze...
Epiboly, the process by which the animally-localized blastoderm spreads vegetally to encapsulate the...
During gastrulation, a set of highly coordinated morphogenetic movements creates the shape and inter...
AbstractWe have analyzed the role of the zebrafish yolk cell in the processes of mesoderm induction ...
AbstractPou5f1/Oct4 is a transcription factor required for pluripotency of embryonic stem cells in m...
AbstractThe homeobox transcription factor Mtx2 is essential for epiboly, the first morphogenetic mov...
The yolk syncytial layer (YSL) is a novel embryonic structure that is unique to teleost fishes like ...
The formation of the vertebrate body plan begins with the segregation of undifferentiated mass of ce...
AbstractMaternal Activin-like proteins, a subgroup of the TGF-β superfamily, play a key role in esta...
AbstractA major approach to the study of development is to compare the phenotypes of normal and muta...
AbstractBackground: In amphibians, the Nieuwkoop center – a primary inducing region – has a central ...
AbstractBackground: Several potentially important regulators of vertebrate endoderm development have...
AbstractRecent studies in mouse suggest that the extraembryonic endoderm has an important role in ea...
SummaryIn vertebrates, extraembryonic tissues can act as signaling centers that impose a reproducibl...
AbstractEpiboly, the first morphogenetic cell movement that occurs in the zebrafish embryo, is the p...
One of the earliest morphogenetic processes in the development of many animals is epiboly. In the ze...
Epiboly, the process by which the animally-localized blastoderm spreads vegetally to encapsulate the...
During gastrulation, a set of highly coordinated morphogenetic movements creates the shape and inter...
AbstractWe have analyzed the role of the zebrafish yolk cell in the processes of mesoderm induction ...
AbstractPou5f1/Oct4 is a transcription factor required for pluripotency of embryonic stem cells in m...
AbstractThe homeobox transcription factor Mtx2 is essential for epiboly, the first morphogenetic mov...
The yolk syncytial layer (YSL) is a novel embryonic structure that is unique to teleost fishes like ...
The formation of the vertebrate body plan begins with the segregation of undifferentiated mass of ce...
AbstractMaternal Activin-like proteins, a subgroup of the TGF-β superfamily, play a key role in esta...
AbstractA major approach to the study of development is to compare the phenotypes of normal and muta...
AbstractBackground: In amphibians, the Nieuwkoop center – a primary inducing region – has a central ...
AbstractBackground: Several potentially important regulators of vertebrate endoderm development have...
AbstractRecent studies in mouse suggest that the extraembryonic endoderm has an important role in ea...
SummaryIn vertebrates, extraembryonic tissues can act as signaling centers that impose a reproducibl...
AbstractEpiboly, the first morphogenetic cell movement that occurs in the zebrafish embryo, is the p...