The Executive Committee of the Society of Toxicologic Pathology (STP) appointed an ad hoc task force to devise and recommend a standard list of tissues to be evaluated histopathologically in repeat-dose toxicity and carcinogenicity studies that are used to support the registration of new pharmaceutical products. The recommended tissue list is intended to be a minimum core list that can be used for all types of repeat-dose toxicity and carcinogenicity studies, regardless of route of administration, species or strain of mammalian laboratory animal, duration, or class of drug to be tested. The resulting recommendations of the task force, presented here, were subsequently reviewed by the STP membership and endorsed by the STP Executive Committe...
1 A three-stage protocol is described for a dose-ranging study which defines the maximum repeatable ...
The Society of Toxicologic Pathology’s Scientific and Regulatory Policy Committee formed a working g...
Supplemental Material, DS1_TPX_10.11770192623319835170 for Scientific and Regulatory Policy Committe...
The evaluation of organ weights in toxicology studies is an integral component in the assessment of ...
The study pathologist provides specialized expertise to the interpretation of the toxicity and safet...
Toxicologic Pathology is the official journal of the Society of Toxicologic Pathology (STP), the Bri...
The Executive Committee of the Society of Toxicologic Pathology (STP) appointed an ad hoc working gr...
In nonrodent toxicity studies that are usually conducted in cynomolgus monkeys or beagle dogs, the a...
In the past decade in vitro tests have been developed that represent a range of anatomic structure f...
Responsible regulatory decisions regarding the fate of new chemicals require careful evaluation of a...
One of the challenges for toxicologic pathologists is to translate the diverse range of morphologic ...
The generation, evaluation, and presentation of data from the ILSI Alternatives to Carcinogenicity T...
The study pathologist provides specialized expertise to the interpretation of the toxicity and safet...
Clinical pathology testing in nonclinical toxicity and safety studies is an important part of safety...
Systemic toxicity testing forms the cornerstone for the safety evaluation of substances. Pressures t...
1 A three-stage protocol is described for a dose-ranging study which defines the maximum repeatable ...
The Society of Toxicologic Pathology’s Scientific and Regulatory Policy Committee formed a working g...
Supplemental Material, DS1_TPX_10.11770192623319835170 for Scientific and Regulatory Policy Committe...
The evaluation of organ weights in toxicology studies is an integral component in the assessment of ...
The study pathologist provides specialized expertise to the interpretation of the toxicity and safet...
Toxicologic Pathology is the official journal of the Society of Toxicologic Pathology (STP), the Bri...
The Executive Committee of the Society of Toxicologic Pathology (STP) appointed an ad hoc working gr...
In nonrodent toxicity studies that are usually conducted in cynomolgus monkeys or beagle dogs, the a...
In the past decade in vitro tests have been developed that represent a range of anatomic structure f...
Responsible regulatory decisions regarding the fate of new chemicals require careful evaluation of a...
One of the challenges for toxicologic pathologists is to translate the diverse range of morphologic ...
The generation, evaluation, and presentation of data from the ILSI Alternatives to Carcinogenicity T...
The study pathologist provides specialized expertise to the interpretation of the toxicity and safet...
Clinical pathology testing in nonclinical toxicity and safety studies is an important part of safety...
Systemic toxicity testing forms the cornerstone for the safety evaluation of substances. Pressures t...
1 A three-stage protocol is described for a dose-ranging study which defines the maximum repeatable ...
The Society of Toxicologic Pathology’s Scientific and Regulatory Policy Committee formed a working g...
Supplemental Material, DS1_TPX_10.11770192623319835170 for Scientific and Regulatory Policy Committe...