ABSTRACT Radiosensitivity as determined by chromosomal aberrations in lymphocytes of patients suffering from fibroadenoma (n=31) and breast cancer (n=41) and was compared with the data from those of healthy individuals (n=10). Lymphocytes from healthy control set of individuals were exposed at G0 stage to different doses (0.5 Gy, 1.0 Gy, 2.0 Gy and 4.0 Gy) of γ-rays. As over 60 % cells remained viable at a dose of 2 Gy, this dose was selected for further experimentation. Lymphocytes were cultured for 48 hours to obtain data from first mitotic metaphases. Frequencies of chromosomal aberrations namely acentric fragments, double minutes, dicentrics and rings were recorded. Lymphocytes of patients with fibroadenoma or breast cancer exhibited hi...
Patients receiving identical radiation treatments experience different effects, from undetectable to...
Radiosensitivity/Human lymphocytes/Breast cancer/Esophageal cancer/Micronuclei. Enhanced chromosomal...
Background. Breast cancer is the leading cancer among South African (SA) women. SA has citizens from...
The age dependency of onset of the disease on chromosomal radiosensitivity of an unselected group of...
The aim: to examine the radiosensitivity of chromosomes of T-lymphocytes in the blood of primary pat...
The dose-response relationship of the chromosomal damage to the blood lymphocytes was obtained from ...
The aim: to examine the radiosensitivity of chromosomes of T-lymphocytes in the blood of primary pat...
In order to assess the usefulness of chromosome aberrations in predicting breast cancer risk, 10 pat...
BACKGROUND AND PURPOSE: There is a need for rapid and reliable tests for the prediction of normal ti...
Background: Acute lymphoblastic leukemia (ALL) is the most common malignancy in childhood, character...
In vitro chromosomal radiosensitivity has been investigated in patients with inherited cancer prone ...
In this study we tried to define incidence and types of chromosomal aberrations (CAs) caused by radi...
A substantial proportion of women with breast cancer exhibit an abnormally high radiosensitivity as ...
Enhanced chromosomal radiosensitivity in breast cancer patients has been demonstrated in several stu...
Purpose: To evaluate the in vitro radiation sensitivity of the peripheral blood lymphocytes obtained...
Patients receiving identical radiation treatments experience different effects, from undetectable to...
Radiosensitivity/Human lymphocytes/Breast cancer/Esophageal cancer/Micronuclei. Enhanced chromosomal...
Background. Breast cancer is the leading cancer among South African (SA) women. SA has citizens from...
The age dependency of onset of the disease on chromosomal radiosensitivity of an unselected group of...
The aim: to examine the radiosensitivity of chromosomes of T-lymphocytes in the blood of primary pat...
The dose-response relationship of the chromosomal damage to the blood lymphocytes was obtained from ...
The aim: to examine the radiosensitivity of chromosomes of T-lymphocytes in the blood of primary pat...
In order to assess the usefulness of chromosome aberrations in predicting breast cancer risk, 10 pat...
BACKGROUND AND PURPOSE: There is a need for rapid and reliable tests for the prediction of normal ti...
Background: Acute lymphoblastic leukemia (ALL) is the most common malignancy in childhood, character...
In vitro chromosomal radiosensitivity has been investigated in patients with inherited cancer prone ...
In this study we tried to define incidence and types of chromosomal aberrations (CAs) caused by radi...
A substantial proportion of women with breast cancer exhibit an abnormally high radiosensitivity as ...
Enhanced chromosomal radiosensitivity in breast cancer patients has been demonstrated in several stu...
Purpose: To evaluate the in vitro radiation sensitivity of the peripheral blood lymphocytes obtained...
Patients receiving identical radiation treatments experience different effects, from undetectable to...
Radiosensitivity/Human lymphocytes/Breast cancer/Esophageal cancer/Micronuclei. Enhanced chromosomal...
Background. Breast cancer is the leading cancer among South African (SA) women. SA has citizens from...