Add to ORKGs, mdisplayeduniquepatterns of centrosomecoloc-alization and controlled TCR-mediated centro-some polarization. Depletion of FMNL1 or DIA1 in cytotoxic lymphocytes abrogated cell-medi-ated killing. Altogether, our results have iden-tifed Arp2/3 complex-independent cytoskeletal reorganization events in T lymphocytes and in-dicate that formins are essential cytoskeletal regulators of centrosome polarity in T cells
Immunological synapse (IS) formation between a T cell and an antigen-presenting cell is accompanied ...
Reorganization of the actin cytoskeleton requires nucleating factors, which initiate actin fiber for...
Immunological synapses are the result of CD8 T cell polarization toward an antigen presenting cell o...
SummaryT cell receptor (TCR)-mediated cytoskeletal reorganization is considered to be actin-related ...
Interactions among immune cells are essential for the development of adaptive immune responses. The ...
International audienceCell polarity is required for the functional specialization of many cell types...
Cell polarity is required for the functional specialization of many cell types including lymphocytes...
© 2021 Calvo and Izquierdo.T cell receptor (TCR) and B cell receptor (BCR) stimulation by antigen pr...
T cell receptor (TCR) stimulation by antigen bound to MHC molecules on an antigen-presen...
Binding of a T cell to an appropriate antigen-presenting cell (APC) induces the rapid reorientation ...
Cytotoxic T lymphocytes (CTLs) are key effector cells in the immune response against viruses and can...
Docking of the centrosome at the plasma membrane directs lytic granules to the immunological synapse...
Docking of the centrosome at the plasma membrane directs lytic granules to the immunological synapse...
T-cell receptor stimulation induces the convergence of multivesicular bodies towards the microtubule...
T cell antigen receptor-proximal signaling components, Rho-family GTPases, and formin proteins DIA1 ...
Immunological synapse (IS) formation between a T cell and an antigen-presenting cell is accompanied ...
Reorganization of the actin cytoskeleton requires nucleating factors, which initiate actin fiber for...
Immunological synapses are the result of CD8 T cell polarization toward an antigen presenting cell o...
SummaryT cell receptor (TCR)-mediated cytoskeletal reorganization is considered to be actin-related ...
Interactions among immune cells are essential for the development of adaptive immune responses. The ...
International audienceCell polarity is required for the functional specialization of many cell types...
Cell polarity is required for the functional specialization of many cell types including lymphocytes...
© 2021 Calvo and Izquierdo.T cell receptor (TCR) and B cell receptor (BCR) stimulation by antigen pr...
T cell receptor (TCR) stimulation by antigen bound to MHC molecules on an antigen-presen...
Binding of a T cell to an appropriate antigen-presenting cell (APC) induces the rapid reorientation ...
Cytotoxic T lymphocytes (CTLs) are key effector cells in the immune response against viruses and can...
Docking of the centrosome at the plasma membrane directs lytic granules to the immunological synapse...
Docking of the centrosome at the plasma membrane directs lytic granules to the immunological synapse...
T-cell receptor stimulation induces the convergence of multivesicular bodies towards the microtubule...
T cell antigen receptor-proximal signaling components, Rho-family GTPases, and formin proteins DIA1 ...
Immunological synapse (IS) formation between a T cell and an antigen-presenting cell is accompanied ...
Reorganization of the actin cytoskeleton requires nucleating factors, which initiate actin fiber for...
Immunological synapses are the result of CD8 T cell polarization toward an antigen presenting cell o...