Effect of Macrophage Overexpression of Murine Liver X Receptor- (LXR-) on Atherosclerosis in LDL-Receptor Deficient Mice

Low-Density Lipoprotein Receptor–Deficient Mice

Hiromi Fujiwara
Theo J. C. Van Berkel
Johan Kuiper
Eva J. A. Van Wanrooij
Arnaud D. Hauer
Paula De Vos
Takeshi Imanishi
Eva J. A. Van Wanrooij
Arnaud D. Hauer
Paula De Vos
Takeshi Imanishi
Hiromi Fujiwara
Theo J. C. Van Berkel
Johan Kuiper

April 2015

at: is onlineArteriosclerosis, Thrombosis, and Vascular Biology Information about subscribing to Sub...

Liver X receptor agonist treatment reduced splanchnic ischemia and reperfusion

Concetta Crisafulli
Rosanna Di Paola
Emanuela Mazzon
Irene Paterniti
Tiziana Genovese
Placido Bramanti
Salvatore Cuzzocrea

January 2010

LXR is another member of the superfamily of nuclear hormone receptors that heterodimerizes with RXR ...

Liver X Receptor–Mediated Induction of Cholesteryl Ester Transfer Protein Expression Is Selectively Impaired in Inflammatory Macrophages

Daniela Lakomy
Anne-laure Sberna
David Masson
Thomas Gautier
Magalie Raveneau
Nicolas Ogier
Anh Thoai Nguyen
Jacques Grober
Bernard Bonnotte
Eric Solary
Laurent Lagrost

October 2016

Objective—Cholesteryl ester transfer protein (CETP) is a target gene for the liver X receptor (LXR)....

Effect of macrophage overexpression of murine liver X receptor-alpha (LXR-alpha) on atherosclerosis in LDL-receptor deficient mice

Teupser, Daniel
Kretzschmar, Daniel
Tennert, Carsten
Burkhardt, Ralph
Wilfert, Wolfgang
Fengler, Dorte
Naumann, Ronald
Sippel, Albrecht E
Thiery, Joachim

January 2008

Background- The nuclear liver X receptor-alpha (LXR-alpha) has been implicated in the regulation of ...

T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice

Terasaka, Naoki
Hiroshima, Ayano
Koieyama, Tadashi
Ubukata, Naoko
Morikawa, Yuka
Nakai, Daisuke
Inaba, Toshimori

February 2003

AbstractLiver X receptors (LXRα and LXRβ) are nuclear receptors, which are important regulators of c...

Lesion Macrophages Are a Key Target for the Antiatherogenic Effects of LXR Agonists

Michelle N. Bradley
Peter Tontonoz

October 2016

The Liver X Receptors (LXR and LXR) are mem-bers of the nuclear hormone receptor superfamily.1These...

Reduced Atherosclerotic Lesions in Mice Deficient for Total or Macrophage-Specific Expression of Scavenger Receptor-A

Sergio Fazio
Macrae F. Linton
Vladimir R. Babaev
Arterioscler Thromb Vasc Biol
Vladimir R. Babaev
Linda A. Gleaves
Kathy J. Carter
Hiroshi Suzuki
Tatsuhiko Kodama
Sergio Fazio
Macrae F. Linton

January 2015

at: is onlineArteriosclerosis, Thrombosis, and Vascular Biology Information about subscribing to Sub...

Activation of liver X receptor decreases atherosclerosis in Ldlr⁻/⁻ mice in the absence of ATP-binding cassette transporters A1 and G1 in myeloid cells

Kappus, Mojdeh S
Murphy, Andrew J
Abramowicz, Sandra
Ntonga, Vusisizwe
Welch, Carrie L
Tall, Alan R
Westerterp, Marit

February 2014

OBJECTIVE: Liver X receptor (LXR) activators decrease atherosclerosis in mice. LXR activators (1) di...

LXR-Dependent Gene Expression Is Important for Macrophage Survival and the Innate Immune Response

Joseph, Sean B.
Bradley, Michelle N.
Castrillo, Antonio
Bruhn, Kevin W.
Mak, Puiying A.
Pei, Liming
Hogenesch, John
O'Connell, Ryan M.
Cheng, Genhong
Saez, Enrique
Miller, Jeffery F.
Tontonoz, Peter

October 2004

AbstractThe liver X receptors (LXRs) are nuclear receptors with established roles in the regulation ...

Liver X Receptor (LXR)- Regulation in LXR-Deficient Mice: Implications for Therapeutic Targeting

Elaine M. Quinet
Dawn A. Savio
Anita R. Halpern
Liang Chen
Gertrude U. Schuster
Jan-åke Gustafsson
Mike D. Basso
Ponnal Nambi

January 2006

The nuclear receptors liver X receptor (LXR) LXR and LXR are differentially expressed ligand-activ...

Disrupting LXRα phosphorylation promotes FoxM1 expression and modulates atherosclerosis by inducing macrophage proliferation

Gage, M C
Becares, N
Louie, R
Waddington, K E
Zhang, Y
Tittanegro, T H
Rodriguez-Lorenzo, S
Jathanna, A
Pourcet, B
Pello, O
De La Rosa, J V
Castrillo, A
Pineda-Torra, I

July 2018

Macrophages are key immune cells for the initiation and development of atherosclerotic lesions. Howe...

Receptor Potentiates Pro-Inflammatory Responses in Macrophages and Exhibits Differential Roles in Atherosclerotic Lesion Development

Garcia Ricardo A.
Yan Mujing
Search Debra
Zhang Rongan
Carson Nancy L.
Ryan Carol S.
Smith-Monroy Constance
Zheng Joanna
Chen Jian
Kong Yan
Tang Huaping
Hellings Samuel E.
Wardwell-Swanson Judith
Dinchuk Joseph E.
Psaltis George C.
Gordon David A.
Glunz Peter W.
Gargalovic Peter S.

October 2014

deficiency on atherosclerosis. deficiency enhanced formation of aneurysms and exhibited a trend tow...

Myeloid-specific deficiency of pregnane X receptor decreases atherosclerosis in LDL receptor-deficient mice [S]

Sui, Yipeng
Meng, Zhaojie
Park, Se-Hyung
Lu, Weiwei
Livelo, Christopher
Chen, Qi
Zhou, Tong
Zhou, Changcheng

May 2020

The pregnane X receptor (PXR) is a nuclear receptor that can be activated by numerous drugs and xeno...

Liver X receptor activation promotes polyunsaturated fatty acid synthesis in macrophages : relevance in the context of atherosclerosis

Varin, Alexis
Thomas, Charles
Ishibashi, Minako
Ménégaut, Louise
Gautier, Thomas
Trousson, Amalia
Bergas, Victoria
Pais de Barros, Jean-Paul
Narce, Michel
Lobaccaro, Jean Marc A
Lagrost, Laurent
Masson, David

May 2015

International audienceOBJECTIVE:Liver X receptors (LXRs) modulate cholesterol and fatty acid homeost...

Liver X receptors as regulators of macrophage inflammatory and metabolic pathways

A-González, Noelia
Castrillo, Antonio

August 2011

AbstractThe liver X receptors (LXRα and LXRβ) are members of the nuclear receptor family of transcri...

Low-Density Lipoprotein Receptor–Deficient Mice

Hiromi Fujiwara
Theo J. C. Van Berkel
Johan Kuiper
Eva J. A. Van Wanrooij
Arnaud D. Hauer
Paula De Vos
Takeshi Imanishi
Eva J. A. Van Wanrooij
Arnaud D. Hauer
Paula De Vos
Takeshi Imanishi
Hiromi Fujiwara
Theo J. C. Van Berkel
Johan Kuiper

April 2015

at: is onlineArteriosclerosis, Thrombosis, and Vascular Biology Information about subscribing to Sub...

Liver X receptor agonist treatment reduced splanchnic ischemia and reperfusion

Concetta Crisafulli
Rosanna Di Paola
Emanuela Mazzon
Irene Paterniti
Tiziana Genovese
Placido Bramanti
Salvatore Cuzzocrea

January 2010

LXR is another member of the superfamily of nuclear hormone receptors that heterodimerizes with RXR ...

Liver X Receptor–Mediated Induction of Cholesteryl Ester Transfer Protein Expression Is Selectively Impaired in Inflammatory Macrophages

Daniela Lakomy
Anne-laure Sberna
David Masson
Thomas Gautier
Magalie Raveneau
Nicolas Ogier
Anh Thoai Nguyen
Jacques Grober
Bernard Bonnotte
Eric Solary
Laurent Lagrost

October 2016

Objective—Cholesteryl ester transfer protein (CETP) is a target gene for the liver X receptor (LXR)....

Effect of macrophage overexpression of murine liver X receptor-alpha (LXR-alpha) on atherosclerosis in LDL-receptor deficient mice

Teupser, Daniel
Kretzschmar, Daniel
Tennert, Carsten
Burkhardt, Ralph
Wilfert, Wolfgang
Fengler, Dorte
Naumann, Ronald
Sippel, Albrecht E
Thiery, Joachim

January 2008

Background- The nuclear liver X receptor-alpha (LXR-alpha) has been implicated in the regulation of ...

T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice

Terasaka, Naoki
Hiroshima, Ayano
Koieyama, Tadashi
Ubukata, Naoko
Morikawa, Yuka
Nakai, Daisuke
Inaba, Toshimori

February 2003

AbstractLiver X receptors (LXRα and LXRβ) are nuclear receptors, which are important regulators of c...

Lesion Macrophages Are a Key Target for the Antiatherogenic Effects of LXR Agonists

Michelle N. Bradley
Peter Tontonoz

October 2016

The Liver X Receptors (LXR and LXR) are mem-bers of the nuclear hormone receptor superfamily.1These...

Reduced Atherosclerotic Lesions in Mice Deficient for Total or Macrophage-Specific Expression of Scavenger Receptor-A

Sergio Fazio
Macrae F. Linton
Vladimir R. Babaev
Arterioscler Thromb Vasc Biol
Vladimir R. Babaev
Linda A. Gleaves
Kathy J. Carter
Hiroshi Suzuki
Tatsuhiko Kodama
Sergio Fazio
Macrae F. Linton

January 2015

at: is onlineArteriosclerosis, Thrombosis, and Vascular Biology Information about subscribing to Sub...

Activation of liver X receptor decreases atherosclerosis in Ldlr⁻/⁻ mice in the absence of ATP-binding cassette transporters A1 and G1 in myeloid cells

Kappus, Mojdeh S
Murphy, Andrew J
Abramowicz, Sandra
Ntonga, Vusisizwe
Welch, Carrie L
Tall, Alan R
Westerterp, Marit

February 2014

OBJECTIVE: Liver X receptor (LXR) activators decrease atherosclerosis in mice. LXR activators (1) di...

LXR-Dependent Gene Expression Is Important for Macrophage Survival and the Innate Immune Response

Joseph, Sean B.
Bradley, Michelle N.
Castrillo, Antonio
Bruhn, Kevin W.
Mak, Puiying A.
Pei, Liming
Hogenesch, John
O'Connell, Ryan M.
Cheng, Genhong
Saez, Enrique
Miller, Jeffery F.
Tontonoz, Peter

October 2004

AbstractThe liver X receptors (LXRs) are nuclear receptors with established roles in the regulation ...

Liver X Receptor (LXR)- Regulation in LXR-Deficient Mice: Implications for Therapeutic Targeting

Elaine M. Quinet
Dawn A. Savio
Anita R. Halpern
Liang Chen
Gertrude U. Schuster
Jan-åke Gustafsson
Mike D. Basso
Ponnal Nambi

January 2006

The nuclear receptors liver X receptor (LXR) LXR and LXR are differentially expressed ligand-activ...

Disrupting LXRα phosphorylation promotes FoxM1 expression and modulates atherosclerosis by inducing macrophage proliferation

Gage, M C
Becares, N
Louie, R
Waddington, K E
Zhang, Y
Tittanegro, T H
Rodriguez-Lorenzo, S
Jathanna, A
Pourcet, B
Pello, O
De La Rosa, J V
Castrillo, A
Pineda-Torra, I

July 2018

Macrophages are key immune cells for the initiation and development of atherosclerotic lesions. Howe...

Receptor Potentiates Pro-Inflammatory Responses in Macrophages and Exhibits Differential Roles in Atherosclerotic Lesion Development

Garcia Ricardo A.
Yan Mujing
Search Debra
Zhang Rongan
Carson Nancy L.
Ryan Carol S.
Smith-Monroy Constance
Zheng Joanna
Chen Jian
Kong Yan
Tang Huaping
Hellings Samuel E.
Wardwell-Swanson Judith
Dinchuk Joseph E.
Psaltis George C.
Gordon David A.
Glunz Peter W.
Gargalovic Peter S.

October 2014

deficiency on atherosclerosis. deficiency enhanced formation of aneurysms and exhibited a trend tow...

Myeloid-specific deficiency of pregnane X receptor decreases atherosclerosis in LDL receptor-deficient mice [S]

Sui, Yipeng
Meng, Zhaojie
Park, Se-Hyung
Lu, Weiwei
Livelo, Christopher
Chen, Qi
Zhou, Tong
Zhou, Changcheng

May 2020

The pregnane X receptor (PXR) is a nuclear receptor that can be activated by numerous drugs and xeno...

Liver X receptor activation promotes polyunsaturated fatty acid synthesis in macrophages : relevance in the context of atherosclerosis

Varin, Alexis
Thomas, Charles
Ishibashi, Minako
Ménégaut, Louise
Gautier, Thomas
Trousson, Amalia
Bergas, Victoria
Pais de Barros, Jean-Paul
Narce, Michel
Lobaccaro, Jean Marc A
Lagrost, Laurent
Masson, David

May 2015

International audienceOBJECTIVE:Liver X receptors (LXRs) modulate cholesterol and fatty acid homeost...

Liver X receptors as regulators of macrophage inflammatory and metabolic pathways

A-González, Noelia
Castrillo, Antonio

August 2011

AbstractThe liver X receptors (LXRα and LXRβ) are members of the nuclear receptor family of transcri...

Low-Density Lipoprotein Receptor–Deficient Mice

Hiromi Fujiwara
Theo J. C. Van Berkel
Johan Kuiper
Eva J. A. Van Wanrooij
Arnaud D. Hauer
Paula De Vos
Takeshi Imanishi
Eva J. A. Van Wanrooij
Arnaud D. Hauer
Paula De Vos
Takeshi Imanishi
Hiromi Fujiwara
Theo J. C. Van Berkel
Johan Kuiper

April 2015

at: is onlineArteriosclerosis, Thrombosis, and Vascular Biology Information about subscribing to Sub...

Liver X receptor agonist treatment reduced splanchnic ischemia and reperfusion

Concetta Crisafulli
Rosanna Di Paola
Emanuela Mazzon
Irene Paterniti
Tiziana Genovese
Placido Bramanti
Salvatore Cuzzocrea

January 2010

LXR is another member of the superfamily of nuclear hormone receptors that heterodimerizes with RXR ...

Liver X Receptor–Mediated Induction of Cholesteryl Ester Transfer Protein Expression Is Selectively Impaired in Inflammatory Macrophages

Daniela Lakomy
Anne-laure Sberna
David Masson
Thomas Gautier
Magalie Raveneau
Nicolas Ogier
Anh Thoai Nguyen
Jacques Grober
Bernard Bonnotte
Eric Solary
Laurent Lagrost

October 2016

Objective—Cholesteryl ester transfer protein (CETP) is a target gene for the liver X receptor (LXR)....

Effect of Macrophage Overexpression of Murine Liver X Receptor- (LXR-) on Atherosclerosis in LDL-Receptor Deficient Mice

Abstract

Extracted data

Effect of Macrophage Overexpression of Murine Liver X Receptor- (LXR-) on Atherosclerosis in LDL-Receptor Deficient Mice

Abstract

Extracted data

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