Add to ORKGMicroarray technology as a method for large-scale gene expression analysis has entered into widespread use in the field of cardiovascular research. This chapter summarizes the appli-cation of arrays to study gene expression profiles of congenital heart diseases, in particular the molecular portrait of tetralogy of Fallot. The sections of this chapter correspond to the several distinct steps of microarray experi-ments. A general introduction to the method, and information on the selection of arrays and preparation of labeled complementary DNA samples are given. A specific focus of the chapter is the experimental design and data analysis. Key Words: Microarray; cDNA array; experimental design; gene expression profiling; te-tralogy of Fallot; ...
Zusammenfassung: In einer genomweiten Genexpressionsstudie wurden normale und fehlgebildete menschli...
Microarray analysis has become a widely available tool for the generation of gene expression data on...
Background: The most typical cardiac abnormality is conotruncal defects (CTDs) in patients with 22q1...
Background We present the first genome-wide cDNA array analysis of human congenitally malformed hear...
Background We present the first genome-wide cDNA array analysis of human congenitally malformed hear...
Cardiovascular disease is the most important cause of morbidity and mortality in developed countries...
ObjectivesThis study was designed to identify a common gene expression signature in dilated cardiomy...
The massive increase in information on the human DNA sequence and the development of new technologi...
Gene expression profiling by microarray technologies has been successfully applied to study the tran...
Despite similar clinical endpoints, heart failure resulting from dilated cardiomyopathy (DCM) or hyp...
Tetralogy of Fallot (TOF) is one of the most common severe congenital heart malformations. Great pro...
Although the contribution of genetics to complex cardiovascular diseases such as atherosclerosis has...
grantor: University of TorontoLarge-scale partial sequencing of randomly selected cDNA clo...
In a genome-wide gene expression study, normal and congenitally malformed human hearts were examined...
<div><p>Tetralogy of Fallot (TOF) is one of the most common severe congenital heart malformations. G...
Zusammenfassung: In einer genomweiten Genexpressionsstudie wurden normale und fehlgebildete menschli...
Microarray analysis has become a widely available tool for the generation of gene expression data on...
Background: The most typical cardiac abnormality is conotruncal defects (CTDs) in patients with 22q1...
Background We present the first genome-wide cDNA array analysis of human congenitally malformed hear...
Background We present the first genome-wide cDNA array analysis of human congenitally malformed hear...
Cardiovascular disease is the most important cause of morbidity and mortality in developed countries...
ObjectivesThis study was designed to identify a common gene expression signature in dilated cardiomy...
The massive increase in information on the human DNA sequence and the development of new technologi...
Gene expression profiling by microarray technologies has been successfully applied to study the tran...
Despite similar clinical endpoints, heart failure resulting from dilated cardiomyopathy (DCM) or hyp...
Tetralogy of Fallot (TOF) is one of the most common severe congenital heart malformations. Great pro...
Although the contribution of genetics to complex cardiovascular diseases such as atherosclerosis has...
grantor: University of TorontoLarge-scale partial sequencing of randomly selected cDNA clo...
In a genome-wide gene expression study, normal and congenitally malformed human hearts were examined...
<div><p>Tetralogy of Fallot (TOF) is one of the most common severe congenital heart malformations. G...
Zusammenfassung: In einer genomweiten Genexpressionsstudie wurden normale und fehlgebildete menschli...
Microarray analysis has become a widely available tool for the generation of gene expression data on...
Background: The most typical cardiac abnormality is conotruncal defects (CTDs) in patients with 22q1...