Coronary Artery Disease Ankle-brachial Index Measured by an Automated Oscillometric Method as a Predictor of Cardiovascular Events in Patients with Coronary Artery Disease

Background: Ankle-brachial index (ABI) measured by conventional Doppler method has been reported to be an independent predictor of adverse cardiovascular events in patients with coronary artery disease (CAD). Recently, a clinical device has been developed to measure ABI by an oscillometric method. It is unclear whether ABI measured by this device can serve as a significant predictor of cardiovascular events in patients with CAD. Materials and Methods: We included 82 patients from our outpatient clinic, who had received coronary angiography examination. ABI was determined in all subjects using the ABI-form (Colin VP1000) device. The lower value of ABI in either of the right or left limbs was used for data analysis. We divided our subjects into two groups with either ABI 0.9 or ABI 0.9 and compared basal characteristics between groups. We followed up these patients for 20.0 3.6 months (range 10 to 26). We analyzed the relationship between ABI and cardiovascular events. Then, we used univariate analysis to determine the significant predictors of cardiovascular events. Finally, we utilized multiple logistic regression analysis to identify the independent predictors of cardiovascular events. Results: There were 14 patients with ABI 0.9 and 68 patients with ABI 0.9. The patients with ABI 0.9 were older and had higher plasma level of uric acid. The prevalence of three-vessel CAD, diabetes mellitus, hypertension, diuretic use, and the risk of cardiovascular death and cardiovascular events were significantly higher in the group of patients with ABI 0.9. In a univariate analysis, cardiovascular events were significantly related to ABI 0.9 (odd