Background: Mammographic breast density is a sig-nificant risk factor for breast cancer. Women with dense tissue accounting for more than 60–75 % of the area of the breast have a 4- to 6-fold increase in their risk of breast cancer, compared to women with little or no breast density. A high circulating level of insulin-like growth factor-I (IGF-I) and low IGF binding protein 3 (IGFBP-3) level have been associated with increased breast density in premenopausal women. Genetic polymorphisms in the IGF1 and IGFBP3 genes may influence breast and serum levels of these growth factors. The aims of this study were to determine whether polymorphic variations in the IGF1 and IGFBP3 genes are associated with breast density, an
Some studies have suggested that insulin-like growth factor (IGF) pathway is related to premenopausa...
High levels of circulating insulin-like growth factor-I (IGF-1), and its major binding protein (IGFB...
High levels of circulating insulin-like growth factor-I (IGF-I) and its major binding protein (IGFBP...
Introduction Mammographic density is one of the strongest risk factors for breast cancer and is bel...
The insulin-like growth factor (IGF) pathway is believed to play a role in carcinogenesis of the mam...
Background and objectives Evidence suggests that circulating IGF-I levels increase mammographic d...
IGF-1 has been shown to promote proliferation of normal epithelial breast cells, and the IGF pathway...
The insulin-like growth factor (IGF) axis plays an essential role in the development of the mammary ...
Insulin-like growth factor-I (IGF-I) and its major binding protein IGFBP-3 have been implicated in b...
Insulin-like growth factor I (IGF-1) stimulates cell proliferation and can enhance the development o...
Insulin-like growth factor I (IGF-I) stimulates cell proliferation and can enhance the development o...
Insulin-like growth factor I (IGF-I) stimulates cell proliferation and can enhance the development o...
Introduction. The IGF system has recently been shown to play an important role in the regulation of ...
1. The journal Cancer Epidemiology, Biomarkers and Prevention is the original source of the material...
Insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) is a major determinant of circulating l...
Some studies have suggested that insulin-like growth factor (IGF) pathway is related to premenopausa...
High levels of circulating insulin-like growth factor-I (IGF-1), and its major binding protein (IGFB...
High levels of circulating insulin-like growth factor-I (IGF-I) and its major binding protein (IGFBP...
Introduction Mammographic density is one of the strongest risk factors for breast cancer and is bel...
The insulin-like growth factor (IGF) pathway is believed to play a role in carcinogenesis of the mam...
Background and objectives Evidence suggests that circulating IGF-I levels increase mammographic d...
IGF-1 has been shown to promote proliferation of normal epithelial breast cells, and the IGF pathway...
The insulin-like growth factor (IGF) axis plays an essential role in the development of the mammary ...
Insulin-like growth factor-I (IGF-I) and its major binding protein IGFBP-3 have been implicated in b...
Insulin-like growth factor I (IGF-1) stimulates cell proliferation and can enhance the development o...
Insulin-like growth factor I (IGF-I) stimulates cell proliferation and can enhance the development o...
Insulin-like growth factor I (IGF-I) stimulates cell proliferation and can enhance the development o...
Introduction. The IGF system has recently been shown to play an important role in the regulation of ...
1. The journal Cancer Epidemiology, Biomarkers and Prevention is the original source of the material...
Insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) is a major determinant of circulating l...
Some studies have suggested that insulin-like growth factor (IGF) pathway is related to premenopausa...
High levels of circulating insulin-like growth factor-I (IGF-1), and its major binding protein (IGFB...
High levels of circulating insulin-like growth factor-I (IGF-I) and its major binding protein (IGFBP...
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