FORMULATION AND ANTI-DIABETIC ACTIVITY STUDIES OF HERBOMINERAL FORMULATION FOR TREATMENT OF DIABETES

ABSTRACT: A number of formulations are marketed globally, claiming to be useful in diabetes & other associated diseases. In present study an attempt has been made to study the comparative efficiency of herbal formulations, for their hypoglycemic activity. The study was conducted on healthy rats randomly distributed streptozotocin (STZ) induced diabetic control & test rat groups. In diabetes induced rats fed with herbomineral formulation 500 mg/Kg & 1000 mg/Kg. The hypoglycemic activity was studied by measuring reduction in blood glucose levels & increased body weight at different time intervals. Present investigation was undertaken to evaluate Antidiabetic activity of herbomineral formulation containing five different herbs & two minerals in streptozotocin (STZ 50 mg/Kg ip single dose) induced diabetic rats. Treatment with formulation F1 (500 mg/Kg) & F2 (1000mg/Kg) by oral administration for 4 weeks produce significant reduction in blood glucose level & increase body weight in diabetic rats. The efficacy of plant extract was comparable with Glibenclamide & Insulin,