Peritonitis-related mortality in patients undergoing chronic peritoneal dialysis. Perit Dial Int 25

Peritonitis is a well-known cause of mortality in perito-neal dialysis (PD) patients. We carried out a retrospective study to disclose the clinical spectrum and risk profile of peri-tonitis-related mortality. We analyzed 693 episodes of infec-tious peritonitis suffered by 565 patients (follow-up 1149 patient-years). Death was the final outcome in 41 cases (5.9% of episodes), peritonitis being directly implicated in 15.2% of the global mortality and 68.5 % of the infectious mortality observed. In 41.5 % of patients with peritonitis-related mor-tality, the immediate cause of death was a cardiovascular event. Highest mortality rates corresponded to fungal (27.5%), enteric (19.3%), and Staphylococcus aureus (15.2%) peritonitis. Multivariate analysis disclosed that the baseline risk of peritonitis-related mortality was significantly higher in female [relative risk (RR) 2.13, 95 % confidenc