Background: In the development of an antimelanoma vaccine, a critical factor is the identification of antigens that induce a strong immune response in humans and that are expressed by melanoma cells in vivo. The aim of this study was to identify candidate anti-gens for such vaccine. Methods: Sixty-nine patients with surgically resected melanomas (American Joint Commis-sion on Cancer [AJCC] stage III) were immunized with a polyvalent vaccine containing multiple melanoma anti-gens. Antimelanoma antibodies gener-ated in the patients ’ sera were used a
Abstract: Generally, cancer is a serious problem no matter what type of cancer, even though we have ...
Immunotherapy of melanoma is aimed to mobilize cytolytic CD8+ T cells playing a central role in prot...
We have pursued our analysis of potential tumor-rejection antigens recognized on human melanoma by a...
Melanogenesis-related proteins play important roles in melanin synthesis and antigenicity of melanom...
Malignant melanomas, although less common than most malignancies, account for 1% of all cancers, and...
Although melanoma accounts for only 4% of skin cancers, it is responsible for 80% of deaths from ski...
The cornerstone of the concept of immunosurveillance in cancer should be the experimental demonstrat...
It is now well established that human melanoma cells express antigens that are recognised by cytolyt...
Six monoclonal antibodies(Mabs) including 4 anti-melanoma, one anti-glioma, and one anti-HLA-DR have...
Summary Clinical observations in the interleukin (IL) 2-based immunotherapies suggest that T cells p...
Progress in human tumor immunology has recently been accelerated by new assays for antigen-specific ...
The antigenicity of melanomas is known better than that of all other human tumors. Melanoma antigens...
Malignant melanoma is an immunogenic tumour capable of inducing a humoral immune response, as shown ...
A human melanoma line genetically modified to release interleukin 4 (IL-4) was utilized to immunize ...
International audienceFifty-nine tumor-infiltrating lymphocyte (TIL) cultures established from melan...
Abstract: Generally, cancer is a serious problem no matter what type of cancer, even though we have ...
Immunotherapy of melanoma is aimed to mobilize cytolytic CD8+ T cells playing a central role in prot...
We have pursued our analysis of potential tumor-rejection antigens recognized on human melanoma by a...
Melanogenesis-related proteins play important roles in melanin synthesis and antigenicity of melanom...
Malignant melanomas, although less common than most malignancies, account for 1% of all cancers, and...
Although melanoma accounts for only 4% of skin cancers, it is responsible for 80% of deaths from ski...
The cornerstone of the concept of immunosurveillance in cancer should be the experimental demonstrat...
It is now well established that human melanoma cells express antigens that are recognised by cytolyt...
Six monoclonal antibodies(Mabs) including 4 anti-melanoma, one anti-glioma, and one anti-HLA-DR have...
Summary Clinical observations in the interleukin (IL) 2-based immunotherapies suggest that T cells p...
Progress in human tumor immunology has recently been accelerated by new assays for antigen-specific ...
The antigenicity of melanomas is known better than that of all other human tumors. Melanoma antigens...
Malignant melanoma is an immunogenic tumour capable of inducing a humoral immune response, as shown ...
A human melanoma line genetically modified to release interleukin 4 (IL-4) was utilized to immunize ...
International audienceFifty-nine tumor-infiltrating lymphocyte (TIL) cultures established from melan...
Abstract: Generally, cancer is a serious problem no matter what type of cancer, even though we have ...
Immunotherapy of melanoma is aimed to mobilize cytolytic CD8+ T cells playing a central role in prot...
We have pursued our analysis of potential tumor-rejection antigens recognized on human melanoma by a...