ANTIBACTERIAL COMPOUNDS ISOLATED FROM BYRSONIMA CRASSIFOLIA

As a part of a project directed toward the discovery of oral antimicrobial compounds from plants, eight known compounds, β-amyrin (1), betulin (2), betulinic acid (3), oleanolic acid (4), quercetin (5), (-)-epicatechin (6), gallic acid (7) and β-sytosterol were isolated from a dichloromethane soluble partition of a methanol extract of Byrsonima crassifolia. All the compounds isolated were evaluated for their antimi-crobial activity against twelve bacteria and Candida albicans. Compounds 1 and 4-7 inhibited the growth of the bacteria with concentrations ranging from 64 to 1088 µg/mL