Syndrome in question

A two-year-old girl, leucodermal, was brought in by her parents, who reported she was born with straight black scalp hair (Figure 1), but, in the sixth month of age, hair started showing tex-tural changes, becoming more curly, and changing color from black to brown and later to blond. The parents also reported loss of hair. Since then, the child presented blond hair that seemed to be uncombed in certain areas, particularly in the occipital region (Figures 2 and 3). There was no associated abnormality. There was also no report of chemical coumpound use, nor a family history of a similar condition. At optical microscopy, the hair seemed nor-mal. The electronic microscopy showed hairs with a shallow and discontinued longitudinal ridge, with elliptical cross sections, with or without chamfer or bevel (reniform) (Figures 4 and 5). Some of the hairs also presented loss of normal cuticular pat-tern, with eroded areas. WHAT IS THIS SYNDROME? Uncombable hair syndrom