IMMERSION REFRACTOMETRY ANALYSIS OF LIVING CELLS

This paper reports a method for measuring the refractive index (RI) of living cells using immersion refractometry integrated with microfluidics. Theoretically, the RI of the cells can be determined to an accuracy of 0.0001. This method features high speed, high accuracy, less damage to cells, ultra integration and real time measurement during long-term cell culture, making it promising for many applications, for example, real-time monitoring of cells