Assessment of a Reference Procedure to Collect and Analyze Glucose in Capillary Whole Blood, Hubert W.

gov) Self-monitoring of blood glucose is used to assist patients with diabetes in achieving and maintaining blood glucose concentrations close to those found in individuals without diabetes. This goal requires that blood glucose monitors meet analytical performance criteria that are appropriate for patient care (1–3). The lack of accuracy of monitors and the resulting variability among monitors limit their use for assessing and maintaining glycemic control (4, 5). No suitable means exists for establishing calibration traceability between a glucose monitor and a reference method. In the absence of a whole-blood glucose refer-ence material, the recommended approach to establishing traceability is to perform split-sample comparisons with patient samples and a reference method (6). This can b