NUMERICAL MODELLING OF BIOSENSORS WITH PERFORATED AND SELECTIVE MEMBRANES1

Abstract. This paper presents a two-dimensional-in-space mathematical model of amperometric biosensors with perforated and selective membranes. The model is based on the diusion equations containing a nonlinear term of the Michaelis-Menten enzymatic reaction. The problem was solved numerically using nite-dierence tech-nique. Using numerical simulation of the biosensors action, the in uence of the ge-ometry of the perforated membrane on the biosensor response was investigated. Key words: modelling, reaction-diusion, simulation, biosensor 1