Abstract: A soluble beta-galactoside-binding lec-tin, galectin-3 has been shown to be involved in cell adhesion and activation of immune cells. Although galectin-3 is known to be expressed in various types of cells, it has not been shown whether galec-tin-3 is expressed in T lymphocytes. We present evidence here that galectin-3 is expressed in acti-vated murine T lymphocytes including CD41 and CD81 T cells but not in resting T cells. Galectin-3 expression was induced by anti-CD3 mAb or mito-gen and enhanced by common g-chain signaling cytokines, IL-2, IL-4, and IL-7, in activated T lymphocytes, whereas the inflammatory cytokines including TNF-a and IFN-g did not. Galectin-3 expression and proliferation were down-regulated by withdrawal of I...
4-1BB is a T cell costimulatory receptor and a member of the tumor necrosis factor receptor superfam...
Galectin-3 (Gal-3) is a β-galactoside binding protein able to modulate both innate and adaptive immu...
The aim of the study was to characterize the features of the subpopulation composition and cytokine-...
We have investigated the function of endogenous galectin-3 in T cells. Galectin-3-deficient (gal3(-/...
Galectin-1 (Gal-1) and galectin-3 (Gal-3) exhibit profound but unique immunomodulatory activities in...
International audienceGalectin-3 (Gal3) is a multifaceted protein which belongs to a family of lecti...
Human CD8(+) tumor-infiltrating T lymphocytes (TIL), in contrast with CD8(+) blood cells, show impai...
BACKGROUND: Galectin-3 is a 31 kD carbohydrate-binding lectin that is over-expressed by many human m...
<p>(A) CD7<sup>−</sup> and CD7<sup>+</sup> T cells were activated by incubation with anti-CD3 mAb pl...
Galectin-3 is a β-galactoside-binding lectin widely expressed on epithelial and hematopoietic cells,...
CD8+ T cells are critical mediators of adaptive immunity, and enhancing their function can promote r...
CD8+ T cells are critical mediators of adaptive immunity, and enhancing their function can promote r...
CD8+ T cells are critical mediators of adaptive immunity, and enhancing their function can promote r...
Galectin-3 (Gal-3) is a \u3b2-galactoside binding protein able to modulate both innate and adaptive ...
4-1BB is a T cell costimulatory receptor and a member of the tumor necrosis factor receptor superfam...
4-1BB is a T cell costimulatory receptor and a member of the tumor necrosis factor receptor superfam...
Galectin-3 (Gal-3) is a β-galactoside binding protein able to modulate both innate and adaptive immu...
The aim of the study was to characterize the features of the subpopulation composition and cytokine-...
We have investigated the function of endogenous galectin-3 in T cells. Galectin-3-deficient (gal3(-/...
Galectin-1 (Gal-1) and galectin-3 (Gal-3) exhibit profound but unique immunomodulatory activities in...
International audienceGalectin-3 (Gal3) is a multifaceted protein which belongs to a family of lecti...
Human CD8(+) tumor-infiltrating T lymphocytes (TIL), in contrast with CD8(+) blood cells, show impai...
BACKGROUND: Galectin-3 is a 31 kD carbohydrate-binding lectin that is over-expressed by many human m...
<p>(A) CD7<sup>−</sup> and CD7<sup>+</sup> T cells were activated by incubation with anti-CD3 mAb pl...
Galectin-3 is a β-galactoside-binding lectin widely expressed on epithelial and hematopoietic cells,...
CD8+ T cells are critical mediators of adaptive immunity, and enhancing their function can promote r...
CD8+ T cells are critical mediators of adaptive immunity, and enhancing their function can promote r...
CD8+ T cells are critical mediators of adaptive immunity, and enhancing their function can promote r...
Galectin-3 (Gal-3) is a \u3b2-galactoside binding protein able to modulate both innate and adaptive ...
4-1BB is a T cell costimulatory receptor and a member of the tumor necrosis factor receptor superfam...
4-1BB is a T cell costimulatory receptor and a member of the tumor necrosis factor receptor superfam...
Galectin-3 (Gal-3) is a β-galactoside binding protein able to modulate both innate and adaptive immu...
The aim of the study was to characterize the features of the subpopulation composition and cytokine-...