Objectives. To compare the in vitro activity of moxifloxacin and ciprofloxacin against 226 nosocomial iso-lates of Acinetobacter baumannii from 44 hospitals in the UK. Methods: MICs of ciprofloxacin and moxifloxacin were determined by Etest. PCR analysis was used to detect chromosomal mutations in the gyrA and parC genes. Isolates resistant to ciprofloxacin and suscep-tible to moxifloxacin were examined for the ability to generate spontaneous moxifloxacin-resistant isolates. Results: Of 226 isolates, 49.1 % were resistant to ciprofloxacin and 39.4 % were moxifloxacin-resistant according to BSAC criteria. Approximately 20 % of isolates resistant to ciprofloxacin remained susceptible to moxifloxacin. A GyrA mutation at Ser-83 was found in all...
ABSTRACT The emergence of fluoroquinolone resistance in nosocomial pathogens has restricted the clin...
This study assesed quinolone resistance in MDR and non-MDR cases. It also analyzed the duration of c...
Background/aim: The increasing prevalence and global spread of difficult-to-treat carbapenem-resista...
Objective(s): We investigated the contribution of gyrA and parC mutational mechanism in decreased ci...
Background: Acinetobacter baumannii and methicillin-resistant Staphylococcus aureus (MRSA) represent...
WOS: 000378184000011PubMed ID: 27175500Acinetobacter baumannii is an opportunistic pathogen which is...
PubMed ID: 27175500Acinetobacter baumannii is an opportunistic pathogen which is one of the most imp...
Abstract Among bacterial species implicated in hospital-acquired infections are the emerging Pan-Dru...
ObjectiveTo determine whether similar mutations to quinolone resistance in the gyrA subunit of DNA g...
100 isolates of Acinetobacter baumannii were collected from different clinical sources including (b...
Background-Acinetobacter has emerged as a nosocomial pathogen. It was sensitive to most antibiotics,...
Nosocomial infections caused by extensively drug-resistant (XDR) or Pan-Drug resistant (PDR) Acineto...
Ciprofloxacin-resistant (CipR) Acinetobacter spp. was associated with a mutation in quinolone resist...
Objectives: To investigate the presence of resistance genes in nosocomial multidrug-resistant (MDR) ...
Background and purpose: Acinetobacter is a pathogen that could cause nosocomial infections. The pres...
ABSTRACT The emergence of fluoroquinolone resistance in nosocomial pathogens has restricted the clin...
This study assesed quinolone resistance in MDR and non-MDR cases. It also analyzed the duration of c...
Background/aim: The increasing prevalence and global spread of difficult-to-treat carbapenem-resista...
Objective(s): We investigated the contribution of gyrA and parC mutational mechanism in decreased ci...
Background: Acinetobacter baumannii and methicillin-resistant Staphylococcus aureus (MRSA) represent...
WOS: 000378184000011PubMed ID: 27175500Acinetobacter baumannii is an opportunistic pathogen which is...
PubMed ID: 27175500Acinetobacter baumannii is an opportunistic pathogen which is one of the most imp...
Abstract Among bacterial species implicated in hospital-acquired infections are the emerging Pan-Dru...
ObjectiveTo determine whether similar mutations to quinolone resistance in the gyrA subunit of DNA g...
100 isolates of Acinetobacter baumannii were collected from different clinical sources including (b...
Background-Acinetobacter has emerged as a nosocomial pathogen. It was sensitive to most antibiotics,...
Nosocomial infections caused by extensively drug-resistant (XDR) or Pan-Drug resistant (PDR) Acineto...
Ciprofloxacin-resistant (CipR) Acinetobacter spp. was associated with a mutation in quinolone resist...
Objectives: To investigate the presence of resistance genes in nosocomial multidrug-resistant (MDR) ...
Background and purpose: Acinetobacter is a pathogen that could cause nosocomial infections. The pres...
ABSTRACT The emergence of fluoroquinolone resistance in nosocomial pathogens has restricted the clin...
This study assesed quinolone resistance in MDR and non-MDR cases. It also analyzed the duration of c...
Background/aim: The increasing prevalence and global spread of difficult-to-treat carbapenem-resista...