Modeling the heat effect of ultrasound in the irradiated tissues

The temperature of the body tissues during ultrasound irradiation depend on the tissue and treatment properties. The newly developed computational model can determine the temperature changes in the skin-muscle-tumor-blood system between different tissue and treatment parameters. The model can calculate with the respiration (315-318K) and denaturing (e.g. HIFU) hyperthermia too. The basic parameters are the geometry, (m); specific heat, (J/gK); density, (g/cm3); heat conductivity, (J/msK); sound velocity (m/s); attenuation coefficient (Np/cm MHz) and the perfusion rate of blood in the different tissue layers (ml/gtissue/min). The effective treatment parameters are the emitted electric output, (J/s); the mechanical efficiency (%); the number (pieces); and the surface area of the transducers (m2); and the area (m2) and temperature (K) of the cooling surfaces. The model calculates many of intermediate data from these. Some of these is the sound path in the different tissues, (m); the blood quantity in the tissue layers, (m); the geometry of the irradiated tissue bodies, (m, cm2, cm3); the acoustic hardness, (Pa s/m); sound reflection and sound transmission occurring at the interfaces, (Np); heat exchanger wall thickness of the irradiated bodies, (m); heat dissipation and heat exchanger surface areas, (m2); flow rate of blood in the tissue