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e.g mellitus. In rare cases, hypoglycaemia can be a produce excess insulin such as pancreatic insulinomas sis factor-a 1998, Lang hromocyto-ctor (IGF)-I ete partially hypoglycaemia (NICTH). Endocrine-Related Cancer (2007) 14 979–993receptor antibodies (in Hodgkin’s disease and otherand treatment.haematological malignancies; Marks & Teale 1998),or ectopic insulin-producing tumours. Second, hypo-glycaemia can be caused by tumour-related factors such as destruction of the liver and adrenal glands by massive tumour infiltration. Finally, hypoglycaemia rarely can be induced by the production of substance