Add to ORKGIron is an essential trace metal in the human diet due to its obligate role in a number of metabolic processes. In the diet, iron is present in a number of different forms, generally described as haem (from haemoglobin and myoglobin in animal tissue) and non-haem iron (including ferric oxides and salts, ferritin and lactoferrin). This review describes the molecular mechanisms that co-ordinate the absorption of iron from the diet and its release into the circulation. While many components of the iron transport pathway have been elucidated, a number of key issues still remain to be resolved. Future work in this area will provide a clearer picture regarding the transcellular fl ux of iron and its regulation by dietary and humoral factors
The human body requires about 1-2 mg of iron per day for its normal functioning, and dietary iron is...
Maintaining physiologic iron concentrations in tissues is critical for metabolism and host defense. ...
<p>Before heme iron can be utilized, heme must be extracted from hemoglobin by proteolytic activity ...
Iron is an essential trace metal in human metabolism. However, imbalances in iron homeostasis are pr...
Iron is the trace element. We get the iron from the dietary sources. The enterocytes lining the uppe...
Iron is an essential trace element, but it is also toxic in excess, and thus mammals have developed ...
Iron is a transition element which has two biologically important oxidation states, +2 and +3. It is...
Iron belongs among the trace elements and its role in humans is irreplaceable. Up to 5 g of iron can...
Iron is essential for fundamental cell functions but is also a catalyst for chemical reactions invol...
Iron is a metal of capital importance in most living organisms. However, man differs from the rest o...
Iron is an essential element involved in many life-necessary processes. Interestingly, in mammals th...
Iron metabolism differs from the metabolism of other metals in that there is no physiologic mechanis...
In the last 20 years, several new genes and proteins involved in iron metabolism in eukaryotes, part...
Iron is a critical metal for several vital biological processes. Most of the body's iron is bound to...
<p>Iron is absorbed from the diet by duodenal enterocytes and transported into the bloodstream, wher...
The human body requires about 1-2 mg of iron per day for its normal functioning, and dietary iron is...
Maintaining physiologic iron concentrations in tissues is critical for metabolism and host defense. ...
<p>Before heme iron can be utilized, heme must be extracted from hemoglobin by proteolytic activity ...
Iron is an essential trace metal in human metabolism. However, imbalances in iron homeostasis are pr...
Iron is the trace element. We get the iron from the dietary sources. The enterocytes lining the uppe...
Iron is an essential trace element, but it is also toxic in excess, and thus mammals have developed ...
Iron is a transition element which has two biologically important oxidation states, +2 and +3. It is...
Iron belongs among the trace elements and its role in humans is irreplaceable. Up to 5 g of iron can...
Iron is essential for fundamental cell functions but is also a catalyst for chemical reactions invol...
Iron is a metal of capital importance in most living organisms. However, man differs from the rest o...
Iron is an essential element involved in many life-necessary processes. Interestingly, in mammals th...
Iron metabolism differs from the metabolism of other metals in that there is no physiologic mechanis...
In the last 20 years, several new genes and proteins involved in iron metabolism in eukaryotes, part...
Iron is a critical metal for several vital biological processes. Most of the body's iron is bound to...
<p>Iron is absorbed from the diet by duodenal enterocytes and transported into the bloodstream, wher...
The human body requires about 1-2 mg of iron per day for its normal functioning, and dietary iron is...
Maintaining physiologic iron concentrations in tissues is critical for metabolism and host defense. ...
<p>Before heme iron can be utilized, heme must be extracted from hemoglobin by proteolytic activity ...