Passive protection by polyclonal antibodies against Bacillus anthracis infection in guinea pigs. Infect. Immun

Convalescent pigs are protected completely against infection with a homologous Actinobacillus pleuropneumoniae strain but incompletely against a heterologous-serotype strain

Cruijsen, A.L.M.
Leengoed, L.A.M.G., van
Ham-Hoffjes, M.
Verheijden, J.H.M.

January 1995

To study whether Actinobacillus pleuropneumoniae induces a species- specific immunity, we infected p...

The detection of protective antigen (PA) associated with spores of Bacillus anthracis and the effects of anti-PA antibodies on spore germination and macrophage interactions

Cote, C.K.
Rossi, C.A.
Kang, A.S.
Morrow, P.R.
Lee, J.S.
Welkos, S.L.
Cote, C.K.
Rossi, C.A.
Kang, A.S.
Morrow, P.R.
Lee, J.S.
Welkos, S.L.

The protective antigen (PA) component of the anthrax toxins is an essential virulence factor of Baci...

Monoclonal Antibody Combinations Prevent Serotype A and Serotype B Inhalational Botulism in a Guinea Pig Model.

Tomic, Milan T
Espinoza, Yero
Martinez, Zachary
Pham, Khanh
Cobb, Ronald R
Snow, Doris M
Earnhart, Christopher G
Pals, Traci
Syar, Emily S
Niemuth, Nancy
Kobs, Dean J
Farr-Jones, Shauna
Marks, James D

April 2019

Botulinum neurotoxins (BoNT) are some of the most toxic proteins known, with a human LD50 of ~1 ng/k...

Immune correlates of protection against anthrax

Fowler, K.
McBride, B. W.
Turnbull, P. C. B.
Baillie, Les

August 1999

Bacillus anthracis protective antigen (PA) has been produced from a recombinant B. subtilis and its ...

Isolation and chimerization of a highly neutralizing antibody conferring passive protection against lethal Bacillus anthracis infection.

Ronit Rosenfeld
Hadar Marcus
Einat Ben-Arie
Bat-El Lachmi
Adva Mechaly
Shaul Reuveny
Orit Gat
Ohad Mazor
Arie Ordentlich

July 2009

Several studies have demonstrated that the passive transfer of protective antigen (PA)-neutralizing ...

Serological Correlate of Protection in Guinea Pigs for a Recombinant Protective Antigen Anthrax Vaccine Produced from Bacillus brevis

Chun, Jeong-Hoon
Choi, On-Jee
Cho, Min-Hee
Hong, Kee-Jong
Seong, Won Keun
Oh, Hee-Bok
Rhie, Gi-Eun

September 2012

AbstractObjectiveRecombinant protective antigen (rPA) is the active pharmaceutical ingredient of a s...

Passive Immunotherapy Protects against Enteric Invasion and Lethal Sepsis in a Murine Model of Gastrointestinal Anthrax

Bruce Huang

September 2015

The principal portal for anthrax infection in natural animal outbreaks is the digestive tract. Enter...

Study of immunization against anthrax with the purified recombinant protective antigen of Bacillus anthracis

Singh, Yogendra
Ivins, Bruce E.
Leppla, Stephen H.

July 1998

Protective antigen (PA) of anthrax toxin is the major component of human anthrax vaccine. Currently ...

Human monoclonal antibodies against anthrax lethal factor and protective antigen act independently to protect against Bacillus anthracis infection and enhance endogenous immunity to anthrax

Albrecht, Mark T.
Li, Han
Williamson, E. Diane
LeButt, Chris S.
Flick-Smith, Helen C.
Quinn, Conrad P.
Westra, Hans
Galloway, Darrell
Mateczun, Alfred
Goldman, Stanley
Groen, Herman
Baillie, Les W. J.

November 2007

The unpredictable nature of bioterrorism and the absence of real-time detection systems have highlig...

Protective efficacy of a recombinant protective antigen against Bacillus anthracis challenge and assessment of immunological markers

McBride, B.
Mogg, A.
Telfer, J. L.
Lever, M. S.
Miller, J.
Turnbull, P. C. B.
Baillie, Les

May 1998

The efficacy of recombinant Bacillus anthracis Protective Antigen (rPA) produced in Bacillus subtili...

Protection of guinea pigs against anthrax infection.

Ronit Rosenfeld (371546)
Hadar Marcus (371547)
Einat Ben-Arie (371549)
Bat-El Lachmi (371551)
Adva Mechaly (371552)
Shaul Reuveny (371553)
Orit Gat (340489)
Ohad Mazor (371555)
Arie Ordentlich (371556)

February 2013

(A) Female Hartley guinea pigs (n = 6 for each group) were i.m. administered with the indicated d...

Bacillus anthracis virulence in Guinea pigs vaccinated with anthrax vaccine adsorbed is linked to plasmid quantities and clonality

Coker, Pamala R
Smith, Kimothy L
Fellows, Patricia F
Rybachuck, Galena
Kousoulas, Konstantin G
Hugh-Jones, Martin E

March 2003

Bacillus anthracis is a bacterial pathogen of great importance, both historically and in the present...

Protection against anthrax with recombinant virus-expressed protective antigen in experimental animals. Infect. Immun

Lauren C. Iacono-connors
Susan L. Welkos
Bruce E. Ivins
Joel M. Dalrymple

January 1991

We previously described the cloning and expression of the protective antigen (PA) gene of Bacillus a...

Obtaining of Polyclonal Antibodies against B. anthracis S-layer Proteins and Study of their Specificity in Enzyme Immunoassay

A. Yu. Goncharova
N. I. Mikshis
O. M. Kudryavtseva
M. F. Bolotnikova
L. V. Novikova
G. G. Krasichkov
T. V. Alenkina
Yu. A. Popov

June 2010

Purified preparations of B. anthracis S-layer proteins - Sap and EA1 were obtained. Developed was th...

Human monoclonal anti-protective antigen antibody completely protects rabbits and is synergistic with ciprofloxacin in protecting mice and guinea pigs against inhalation anthrax

Peterson, J.W.
Comer, J.E.
Noffsinger, D.M.
Wenglikowski, A.
Walberg, K.G.
Chatuev, B.M.
Chopra, A.K.
Stanberry, L.R.
Kang, A.S.
Scholz, W.W.
Sircar, J.
Peterson, J.W.
Comer, J.E.
Noffsinger, D.M.
Wenglikowski, A.
Walberg, K.G.
Chatuev, B.M.
Chopra, A.K.
Stanberry, L.R.
Kang, A.S.
Scholz, W.W.
Sircar, J.

Prevention of inhalation anthrax requires early and extended antibiotic therapy, and therefore, alte...

Convalescent pigs are protected completely against infection with a homologous Actinobacillus pleuropneumoniae strain but incompletely against a heterologous-serotype strain

Cruijsen, A.L.M.
Leengoed, L.A.M.G., van
Ham-Hoffjes, M.
Verheijden, J.H.M.

January 1995

To study whether Actinobacillus pleuropneumoniae induces a species- specific immunity, we infected p...

The detection of protective antigen (PA) associated with spores of Bacillus anthracis and the effects of anti-PA antibodies on spore germination and macrophage interactions

Cote, C.K.
Rossi, C.A.
Kang, A.S.
Morrow, P.R.
Lee, J.S.
Welkos, S.L.
Cote, C.K.
Rossi, C.A.
Kang, A.S.
Morrow, P.R.
Lee, J.S.
Welkos, S.L.

The protective antigen (PA) component of the anthrax toxins is an essential virulence factor of Baci...

Monoclonal Antibody Combinations Prevent Serotype A and Serotype B Inhalational Botulism in a Guinea Pig Model.

Tomic, Milan T
Espinoza, Yero
Martinez, Zachary
Pham, Khanh
Cobb, Ronald R
Snow, Doris M
Earnhart, Christopher G
Pals, Traci
Syar, Emily S
Niemuth, Nancy
Kobs, Dean J
Farr-Jones, Shauna
Marks, James D

April 2019

Botulinum neurotoxins (BoNT) are some of the most toxic proteins known, with a human LD50 of ~1 ng/k...

Immune correlates of protection against anthrax

Fowler, K.
McBride, B. W.
Turnbull, P. C. B.
Baillie, Les

August 1999

Bacillus anthracis protective antigen (PA) has been produced from a recombinant B. subtilis and its ...

Isolation and chimerization of a highly neutralizing antibody conferring passive protection against lethal Bacillus anthracis infection.

Ronit Rosenfeld
Hadar Marcus
Einat Ben-Arie
Bat-El Lachmi
Adva Mechaly
Shaul Reuveny
Orit Gat
Ohad Mazor
Arie Ordentlich

July 2009

Several studies have demonstrated that the passive transfer of protective antigen (PA)-neutralizing ...

Serological Correlate of Protection in Guinea Pigs for a Recombinant Protective Antigen Anthrax Vaccine Produced from Bacillus brevis

Chun, Jeong-Hoon
Choi, On-Jee
Cho, Min-Hee
Hong, Kee-Jong
Seong, Won Keun
Oh, Hee-Bok
Rhie, Gi-Eun

September 2012

AbstractObjectiveRecombinant protective antigen (rPA) is the active pharmaceutical ingredient of a s...

Passive Immunotherapy Protects against Enteric Invasion and Lethal Sepsis in a Murine Model of Gastrointestinal Anthrax

Bruce Huang

September 2015

The principal portal for anthrax infection in natural animal outbreaks is the digestive tract. Enter...

Study of immunization against anthrax with the purified recombinant protective antigen of Bacillus anthracis

Singh, Yogendra
Ivins, Bruce E.
Leppla, Stephen H.

July 1998

Protective antigen (PA) of anthrax toxin is the major component of human anthrax vaccine. Currently ...

Human monoclonal antibodies against anthrax lethal factor and protective antigen act independently to protect against Bacillus anthracis infection and enhance endogenous immunity to anthrax

Albrecht, Mark T.
Li, Han
Williamson, E. Diane
LeButt, Chris S.
Flick-Smith, Helen C.
Quinn, Conrad P.
Westra, Hans
Galloway, Darrell
Mateczun, Alfred
Goldman, Stanley
Groen, Herman
Baillie, Les W. J.

November 2007

The unpredictable nature of bioterrorism and the absence of real-time detection systems have highlig...

Protective efficacy of a recombinant protective antigen against Bacillus anthracis challenge and assessment of immunological markers

McBride, B.
Mogg, A.
Telfer, J. L.
Lever, M. S.
Miller, J.
Turnbull, P. C. B.
Baillie, Les

May 1998

The efficacy of recombinant Bacillus anthracis Protective Antigen (rPA) produced in Bacillus subtili...

Protection of guinea pigs against anthrax infection.

Ronit Rosenfeld (371546)
Hadar Marcus (371547)
Einat Ben-Arie (371549)
Bat-El Lachmi (371551)
Adva Mechaly (371552)
Shaul Reuveny (371553)
Orit Gat (340489)
Ohad Mazor (371555)
Arie Ordentlich (371556)

February 2013

(A) Female Hartley guinea pigs (n = 6 for each group) were i.m. administered with the indicated d...

Bacillus anthracis virulence in Guinea pigs vaccinated with anthrax vaccine adsorbed is linked to plasmid quantities and clonality

Coker, Pamala R
Smith, Kimothy L
Fellows, Patricia F
Rybachuck, Galena
Kousoulas, Konstantin G
Hugh-Jones, Martin E

March 2003

Bacillus anthracis is a bacterial pathogen of great importance, both historically and in the present...

Protection against anthrax with recombinant virus-expressed protective antigen in experimental animals. Infect. Immun

Lauren C. Iacono-connors
Susan L. Welkos
Bruce E. Ivins
Joel M. Dalrymple

January 1991

We previously described the cloning and expression of the protective antigen (PA) gene of Bacillus a...

Obtaining of Polyclonal Antibodies against B. anthracis S-layer Proteins and Study of their Specificity in Enzyme Immunoassay

A. Yu. Goncharova
N. I. Mikshis
O. M. Kudryavtseva
M. F. Bolotnikova
L. V. Novikova
G. G. Krasichkov
T. V. Alenkina
Yu. A. Popov

June 2010

Purified preparations of B. anthracis S-layer proteins - Sap and EA1 were obtained. Developed was th...

Human monoclonal anti-protective antigen antibody completely protects rabbits and is synergistic with ciprofloxacin in protecting mice and guinea pigs against inhalation anthrax

Peterson, J.W.
Comer, J.E.
Noffsinger, D.M.
Wenglikowski, A.
Walberg, K.G.
Chatuev, B.M.
Chopra, A.K.
Stanberry, L.R.
Kang, A.S.
Scholz, W.W.
Sircar, J.
Peterson, J.W.
Comer, J.E.
Noffsinger, D.M.
Wenglikowski, A.
Walberg, K.G.
Chatuev, B.M.
Chopra, A.K.
Stanberry, L.R.
Kang, A.S.
Scholz, W.W.
Sircar, J.

Prevention of inhalation anthrax requires early and extended antibiotic therapy, and therefore, alte...

Convalescent pigs are protected completely against infection with a homologous Actinobacillus pleuropneumoniae strain but incompletely against a heterologous-serotype strain

Cruijsen, A.L.M.
Leengoed, L.A.M.G., van
Ham-Hoffjes, M.
Verheijden, J.H.M.

January 1995

To study whether Actinobacillus pleuropneumoniae induces a species- specific immunity, we infected p...

The detection of protective antigen (PA) associated with spores of Bacillus anthracis and the effects of anti-PA antibodies on spore germination and macrophage interactions

Cote, C.K.
Rossi, C.A.
Kang, A.S.
Morrow, P.R.
Lee, J.S.
Welkos, S.L.
Cote, C.K.
Rossi, C.A.
Kang, A.S.
Morrow, P.R.
Lee, J.S.
Welkos, S.L.

The protective antigen (PA) component of the anthrax toxins is an essential virulence factor of Baci...

Monoclonal Antibody Combinations Prevent Serotype A and Serotype B Inhalational Botulism in a Guinea Pig Model.

Tomic, Milan T
Espinoza, Yero
Martinez, Zachary
Pham, Khanh
Cobb, Ronald R
Snow, Doris M
Earnhart, Christopher G
Pals, Traci
Syar, Emily S
Niemuth, Nancy
Kobs, Dean J
Farr-Jones, Shauna
Marks, James D

April 2019

Botulinum neurotoxins (BoNT) are some of the most toxic proteins known, with a human LD50 of ~1 ng/k...

Passive protection by polyclonal antibodies against Bacillus anthracis infection in guinea pigs. Infect. Immun

Abstract

Extracted data

Passive protection by polyclonal antibodies against Bacillus anthracis infection in guinea pigs. Infect. Immun

Abstract

Extracted data

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