Imaging Modalities

the potential applicability to the study of lung pathophysiology in small-animal models. The goals of the conference were as follows: (1) to summarize the current state of small-animal models of lung pathophysiology and their applicability to human disease; (2) to identify all potential modes of noninvasive imaging; (3) to explore the potential for current and future applications; (4) to discuss and debate current controversies; and (5) to identify future research directions and opportunities for, and applications of, imaging technology to facilitate the use of small-animal models for the study of lung diseases. The first part of the workshop focused on the current state of knowledge of mouse models with an emphasis on ‘‘What are the big questions?’ ’ and ‘‘How good are the models?’ ’ Presentations described four major animal model systems of lung disease: (1) reactive airway disease, (2) chronic obstructive pulmonary diseas