Electrocardiographic Gated 99mTc-MIBI SPECT for Functional Assessment of Patients After Coronary Artery Bypass Surgery: Comparison

Abnormal septal motion after coronary artery bypass graft sur-gery (CABG) is a common finding. This study was undertaken to investigate the change in various global and regional ventricular function parameters measured by gated myocardial perfusion SPECT after surgery and to determine which quantitative pa-rameter of WT and WM is more appropriate for the evaluation of regional cardiac function, especially in the septum of patients with CABG. Methods: Before and 3 to 5 wk after CABG (all patients underwent at least 1 bypass grafting to the left anterior descending coronary artery), 35 patients (28 men, 7 women) underwent gated SPECT using 99mTc-methoxyisobutylisonitrile. Quantitative global and regional ventricular functional analysis was performed using quantitative gated SPECT software. Re-sults: Global ejection fraction did not change (59.3 % 16.0% to 60.5 % 14.5%, P 0.24). However, end-diastolic an