MAJOR ARTICLE Predictors and Outcomes of Candiduria in Renal Transplant Recipients

Background. The epidemiology of candiduria in renal transplantation is unknown. Methods. We performed a nested case-control study to evaluate the epidemiology of candiduria in renal transplant recipients at the University of Wisconsin (Madison) over an 8-year period. Results. Renal transplantations were performed on 1738 patients during this period, 192 of whom had 276 episodes of candiduria. Candida glabrata, which was recovered from 98 (51%) of 192 case patients, was the most common pathogen identified. Most case patients were asymptomatic. Independent predictors of candiduria were female sex (odds ratio [OR], 12.5; 95 % confidence interval [CI], 6.7-23.0), intensive care unit admission (OR, 8.8; 95 % CI, 2.3-35-.0), antibiotic use during the month before candiduria (OR, 3.8; 95 % CI, 1.7-8.3), presenc