An earlier study revealed that 24R,25-dihydroxyvitamin D3 (24R,25(OH)2D3) inhibits the rapid actions of 1,25(OH)2D3 on stimulation of calcium transport in per-fused duodena, as well as activation of protein kinases C and A. In the present work, a specific binding protein (24,25-BP) has been identified and partially characterized. Percoll-gradient resolution of differential centrifugation fractions from mucosal homogenates revealed the highest levels of specific [3H]24R,25(OH)2D3 binding to be in lysosomes (approximately eight to tenfold greater than in basal lateral membrane fractions). Incubation of isolated enterocytes with 6·5 nM [3H]24R,25(OH)2D3 for 10 s also demonstrated targeting of the steroid to lysosomal fractions. Using freshly i...
1,25-Dihydroxyvitamin D3 [1,25(OH)2D31 increases intestinal calcium absorption through events that i...
It is now accepted that 1,25(OH)2D3 mediates its rapid actions on the control of phosphate and calci...
AbstractVitamin D3 and 1,25-dihydroxyvitamin D3 raise (Na+ + K+)-ATPase activity (ouabain-sensitive ...
Vitamin D is hydroxylated to form several active metabolites, of these, 1,25- dihydroxyvitamin D3 [1...
R ECENTLY, it has been shown that the administration of vitamin D3 to a rachitic animal results in t...
function have been briefly described, with emphasis given to a vitamin D-induced calcium-binding pro...
The work reported in this thesis is mainly concerned with the influence of vitamin D on the subcell...
Avian intestinal cytosoluble receptors for 1,25-dihydroxyvitamin D₃ (1,25(OH)₂D₃) were subjected to ...
AbstractThe binding of 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] to its chick intestinal receptor does ...
The presence of a specific receptor for 1,25-dihydroxy-vitamin D3 was investigated in myoblasts rele...
A method developed initially for the detection of high-affinity binding of glucocorticoids in the cy...
The steroid hormone 1alpha,25(OH)(2)-vitamin D-3 (1,25D) regulates gene transcription through a nucl...
Abstract: We have shown that the 1,25D3-MARRS receptor is necessary for the rapid, pre-genomic effec...
In this report we confirm that the putative vitamin D response element (VDRE), located between -320 ...
124 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1984.This thesis reports the isola...
1,25-Dihydroxyvitamin D3 [1,25(OH)2D31 increases intestinal calcium absorption through events that i...
It is now accepted that 1,25(OH)2D3 mediates its rapid actions on the control of phosphate and calci...
AbstractVitamin D3 and 1,25-dihydroxyvitamin D3 raise (Na+ + K+)-ATPase activity (ouabain-sensitive ...
Vitamin D is hydroxylated to form several active metabolites, of these, 1,25- dihydroxyvitamin D3 [1...
R ECENTLY, it has been shown that the administration of vitamin D3 to a rachitic animal results in t...
function have been briefly described, with emphasis given to a vitamin D-induced calcium-binding pro...
The work reported in this thesis is mainly concerned with the influence of vitamin D on the subcell...
Avian intestinal cytosoluble receptors for 1,25-dihydroxyvitamin D₃ (1,25(OH)₂D₃) were subjected to ...
AbstractThe binding of 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] to its chick intestinal receptor does ...
The presence of a specific receptor for 1,25-dihydroxy-vitamin D3 was investigated in myoblasts rele...
A method developed initially for the detection of high-affinity binding of glucocorticoids in the cy...
The steroid hormone 1alpha,25(OH)(2)-vitamin D-3 (1,25D) regulates gene transcription through a nucl...
Abstract: We have shown that the 1,25D3-MARRS receptor is necessary for the rapid, pre-genomic effec...
In this report we confirm that the putative vitamin D response element (VDRE), located between -320 ...
124 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1984.This thesis reports the isola...
1,25-Dihydroxyvitamin D3 [1,25(OH)2D31 increases intestinal calcium absorption through events that i...
It is now accepted that 1,25(OH)2D3 mediates its rapid actions on the control of phosphate and calci...
AbstractVitamin D3 and 1,25-dihydroxyvitamin D3 raise (Na+ + K+)-ATPase activity (ouabain-sensitive ...