Add to ORKG4To whom correspondence should be addressed Allelotype and replication error (RER) phenotype analyses were performed to clarify the pathogenetic significance of inactivation of tumor suppressor genes and genomic instability in the genesis and progression of small cell lung carcinoma (SCLC). We examined 37 cases of SCLC for loss of heterozygosity (LOH) and microsatellite instability at 49 loci on all 39 nonacrocentric chromosomal arms. LOH was frequently (.70%) detected on chromosomes 3
[[abstract]]We extensively allelotyped a panel of 71 microdissected primary surgically resected non ...
BACKGROUND. Lung carcinoma is a leading cause of cancer deaths worldwide. To better understand this ...
Lung cancer is the leading cause of cancer-related deaths in North America and Europe for both men ...
BACKGROUND: Genomic instability, which is manifested by the replication error (RER) phenotype, has b...
Microsatellites are highly polymorphic, short-tandem repeat sequences dispersed throughout the genom...
Allelic loss is a hallmark of tumor suppressor gene (TSG) inactivation. We have allelotyped 29 paire...
Lung cancer is the worldwide leading cause of death from cancer and has been shown to be a heterogen...
Recent cytogenetic studies have indicated that loss of the long arm of chromosome 4 is a frequent ev...
As chromosomes 2p and 3p are frequent targets for genomic instability in lung cancer, we have addres...
We generated allelotypes of 38 methylene chloride-induced lung carcinomas from female C57BL/6J x C3H...
Background Recent cytogenetic studies indicated that loss of the long arm of chromosome 5 is a freq...
In childhood malignancies such as retinoblastoma and Wilms tumour, of which both familial and sporad...
It is now widely accepted that human carcinogenesis is a multi-step process and phenotypic changes d...
We investigated the frequency and clinical significance of loss of heterozygosity (LOH) at the APC, ...
We performed whole-genome sequencing (WGS) of a case of early-stage small-cell lung cancer (SCLC) to...
[[abstract]]We extensively allelotyped a panel of 71 microdissected primary surgically resected non ...
BACKGROUND. Lung carcinoma is a leading cause of cancer deaths worldwide. To better understand this ...
Lung cancer is the leading cause of cancer-related deaths in North America and Europe for both men ...
BACKGROUND: Genomic instability, which is manifested by the replication error (RER) phenotype, has b...
Microsatellites are highly polymorphic, short-tandem repeat sequences dispersed throughout the genom...
Allelic loss is a hallmark of tumor suppressor gene (TSG) inactivation. We have allelotyped 29 paire...
Lung cancer is the worldwide leading cause of death from cancer and has been shown to be a heterogen...
Recent cytogenetic studies have indicated that loss of the long arm of chromosome 4 is a frequent ev...
As chromosomes 2p and 3p are frequent targets for genomic instability in lung cancer, we have addres...
We generated allelotypes of 38 methylene chloride-induced lung carcinomas from female C57BL/6J x C3H...
Background Recent cytogenetic studies indicated that loss of the long arm of chromosome 5 is a freq...
In childhood malignancies such as retinoblastoma and Wilms tumour, of which both familial and sporad...
It is now widely accepted that human carcinogenesis is a multi-step process and phenotypic changes d...
We investigated the frequency and clinical significance of loss of heterozygosity (LOH) at the APC, ...
We performed whole-genome sequencing (WGS) of a case of early-stage small-cell lung cancer (SCLC) to...
[[abstract]]We extensively allelotyped a panel of 71 microdissected primary surgically resected non ...
BACKGROUND. Lung carcinoma is a leading cause of cancer deaths worldwide. To better understand this ...
Lung cancer is the leading cause of cancer-related deaths in North America and Europe for both men ...