Dementia and Depression in End Stage Renal Disease: Comparison between Hemodialysis and Continuous Ambulatory Peritoneal Dialysis

Dementia is a common condition among elderly and chronic illness including chronic renal disease(1-6). Recently, mean population age has Objectives: To determine the prevalence, risk factors of dementia and depression in end stage renal disease (ESRD) who were treated with hemodialysis (HD) compared with those who had continuous ambulatory peritoneal dialysis (CAPD). Material and Method: A cross-sectional study was conducted on 90 ESRD patients (60 HD and 30 CAPD groups). The authors reviewed the demographic data, investigation results. Thai Mental State Examination, DSM IV criteria and Thai Depression Inventory were interviewed to determine dementia and depression respectively. Results: Both prevalence of dementia and depression in ESRD on continuous dialysis were 6.7 %. In the HD group had 8.3 % prevalence of dementia and 6.7 % of depression, whereas there was 3.3 % of dementia and 6.7 % of depression in the CAPD group. The severity of depression in the present study was mild to moderate (6.7%) and no major depression was seen. The significant risk factors for dementia were age ≥ 60 years (p=0.003), Education < 10 years (p=0.037) and female sex (p=0.036). Th