Context: Reduction in adult neurogenesis has been pro-posed as amechanism for onset of depression. Semaphor-ins and their coreceptors, plexins, have been implicated in nervous system development and in adult neurogen-esis. A recent genomewide association study of schizo-phrenia identified a variant of the gene encoding plexin A2 (PLXNA2) to be most consistently associated across study samples. Common genetic liabilities have been re-ported between psychiatric and psychological measures, but few examples exist of common genetic variants. Objective: To perform a genetic association study be-tween 6 single nucleotide polymorphisms from the PLXNA2 gene (rs3736963, rs2767565, rs752016, rs1327175, rs2478813, and rs716461) and anxiety, de-pression...
Most psychiatric disorders are moderately to highly heritable. The degree to which genetic variation...
Background: Twin and adoption studies have consistently implicated genes in the etiology of schizoph...
Some individuals are endowed with a biology that renders them more reactive to novelty and potential...
Context: Reduction in adult neurogenesis has been pro-posed as amechanism for onset of depression. S...
Context: Reduction in adult neurogenesis has been proposed as a mechanism for onset of depression. S...
Context: People meeting diagnostic criteria for anxiety or depressive disorders tend to score high o...
The discovery of genetic factors that contribute to schizophrenia susceptibility is a key challenge ...
Genome-wide association study of behavioural and psychiatric features in human prion disease AGB Tho...
Schizophrenia is a highly heritable disorder with a polygenic pattern of inheritance and a populatio...
Genome-wide association studies (GWASs) have identified a number of susceptibility genes for schizop...
CONTEXT: Anxiety disorders are common, with a lifetime prevalence of 20% in the U.S., and are respon...
Context: People meeting diagnostic criteria for anxiety or depressive disorders tend to score high o...
To investigate the phenotypic and genetic overlap between anxiety and depression symp-toms in an adm...
OBJECTIVES: Co-morbidity between depression and anxiety disorders is common. In this study we define...
Personality traits are summarized by five broad dimensions with pervasive influences on major life o...
Most psychiatric disorders are moderately to highly heritable. The degree to which genetic variation...
Background: Twin and adoption studies have consistently implicated genes in the etiology of schizoph...
Some individuals are endowed with a biology that renders them more reactive to novelty and potential...
Context: Reduction in adult neurogenesis has been pro-posed as amechanism for onset of depression. S...
Context: Reduction in adult neurogenesis has been proposed as a mechanism for onset of depression. S...
Context: People meeting diagnostic criteria for anxiety or depressive disorders tend to score high o...
The discovery of genetic factors that contribute to schizophrenia susceptibility is a key challenge ...
Genome-wide association study of behavioural and psychiatric features in human prion disease AGB Tho...
Schizophrenia is a highly heritable disorder with a polygenic pattern of inheritance and a populatio...
Genome-wide association studies (GWASs) have identified a number of susceptibility genes for schizop...
CONTEXT: Anxiety disorders are common, with a lifetime prevalence of 20% in the U.S., and are respon...
Context: People meeting diagnostic criteria for anxiety or depressive disorders tend to score high o...
To investigate the phenotypic and genetic overlap between anxiety and depression symp-toms in an adm...
OBJECTIVES: Co-morbidity between depression and anxiety disorders is common. In this study we define...
Personality traits are summarized by five broad dimensions with pervasive influences on major life o...
Most psychiatric disorders are moderately to highly heritable. The degree to which genetic variation...
Background: Twin and adoption studies have consistently implicated genes in the etiology of schizoph...
Some individuals are endowed with a biology that renders them more reactive to novelty and potential...