Consanguinity Associated with Child and Adult Mortality in 24 Asian and African Countries, an Ecological Study

Background: Although numerous studies have found deleterious effects of inbreeding on childhood and pre-reproductive mortality, one question remains inadequately addressed: Dose inbreeding lead to increased childhood mortality rates in countries with high level of consanguinity? Methods: To evaluate the public health impact of inbreeding on offspring mortality, the association between mean of inbreeding coefficient (α) and sex specific child and adult mortality rates in 24 countries from Asia and Africa was analyzed. Results: Statistical analysis showed that countries with relatively higher rates of consanguineous marriages have higher mortality rates than the countries with lower consanguinity rates. Also, countries with relatively higher GDP per capita have lower mortality rates. After controlling the GDP per capita, significant positiv