n

t o io nar pr (2-ethylhexyl) phthalate (MEHP), the active metabolite of the frequently used plasticizer di-(2-ethylhexyl) phthalate (DEHP), on gonadal hypospadias, cryptorchidism, and testicular cancer has one of themost frequently used phthalates, and inWestern and/or reproductive toxicity in a number of mammalian mono-(2-ethylhexyl) phthalate (MEHP), is thought to be Europe it accounts for w30 % of all plasticizer usage.DOI: 10.1530/REP-07-0460It is considered to have a low acute toxicity in several q 2008 Society for Reproduction and Fertilitythe active agent in testicular (Sjoberg et al. 1986) aswell as ovarian toxicity (Davis et al. 1994b).When ingested orally,increased during the last decades in several Western countries (Lottrup et al. 2006). These disorders are hypothesized to be manifestations of the same under-lying prenatal disturbance, the testicular dysgenesi