heat shock protein 70 (HSP70); heme oxygenase-1 (HSP32); platelet-derived growth factor (PDGF); glial cells; differentiation; C6 Heat shock proteins (HSPs) are immediately expressed in neuronal and glial cells under various stressful conditions and play a protective role through molecular chaperones. We investigated the characteristics of the induction manner of heme oxygenase-1 (HO-1) and HSP70 in rat C6 glioblastoma cells. In heat treatment (42'C for 30 min), C6 cells expressed high level of HO-1 and HSP70 mRNAs Within 30-60 min, and their proteins at 3 hrs. Heat-induced expressions of HSPs mRNAs were completely inhibited with actinomycin D, suggesting the transcriptional regulation. Oxygen-glucose deprivation (OGD), cystine-free (in...
Cultured purified oligodendroglia and astroglia exposed to heat stress (45 °C, 10 or 20 min) synthes...
In response to many environmental and pathophysiologic stressful stimuli, cells undergo a stress res...
Heat shock/ stress proteins (HSPs) are crucial for maintenance of cellular homeostasis during normal...
Induction of heat shock proteins (Hsps), especially the 70-kDa family, is well observed in nervous t...
Inflammation is an important event in ischemic injury. These immune responses begin with the express...
The 70 kDa heat shock protein (Hsp70) is synthesized in response to a variety of stresses, including...
Inflammation is an important event in ischemic injury. These immune responses begin with the express...
Heat shock proteins (Hsps) represent the most evolutionarily ancient, conserved, and universal syste...
In this study we investigated the time course, cell-type and stress-specific expression of hsp70 mRN...
Heat shock proteins (Hsps) are induced by heat shock via heat shock factor proteins binding to heat ...
In response to a variety of hyperthermic treatments, rat embryonic fibroblasts synthesize heat shock...
We previously showed that overexpressing the 70-kDa inducible heat shock protein in primary astrocyt...
Induction of heat shock protein 70 protects mesangial cells against oxidative injury. The heat shock...
Causes of lower induction of Hsp70 in neurons during heat shock are still a matter of debate. To fur...
In response to stressful stimuli, cells respond by inducing a set of heat shock (stress) proteins (h...
Cultured purified oligodendroglia and astroglia exposed to heat stress (45 °C, 10 or 20 min) synthes...
In response to many environmental and pathophysiologic stressful stimuli, cells undergo a stress res...
Heat shock/ stress proteins (HSPs) are crucial for maintenance of cellular homeostasis during normal...
Induction of heat shock proteins (Hsps), especially the 70-kDa family, is well observed in nervous t...
Inflammation is an important event in ischemic injury. These immune responses begin with the express...
The 70 kDa heat shock protein (Hsp70) is synthesized in response to a variety of stresses, including...
Inflammation is an important event in ischemic injury. These immune responses begin with the express...
Heat shock proteins (Hsps) represent the most evolutionarily ancient, conserved, and universal syste...
In this study we investigated the time course, cell-type and stress-specific expression of hsp70 mRN...
Heat shock proteins (Hsps) are induced by heat shock via heat shock factor proteins binding to heat ...
In response to a variety of hyperthermic treatments, rat embryonic fibroblasts synthesize heat shock...
We previously showed that overexpressing the 70-kDa inducible heat shock protein in primary astrocyt...
Induction of heat shock protein 70 protects mesangial cells against oxidative injury. The heat shock...
Causes of lower induction of Hsp70 in neurons during heat shock are still a matter of debate. To fur...
In response to stressful stimuli, cells respond by inducing a set of heat shock (stress) proteins (h...
Cultured purified oligodendroglia and astroglia exposed to heat stress (45 °C, 10 or 20 min) synthes...
In response to many environmental and pathophysiologic stressful stimuli, cells undergo a stress res...
Heat shock/ stress proteins (HSPs) are crucial for maintenance of cellular homeostasis during normal...