Spectroscopic Characterisation and Biological Applications of Organotin(IV) Derivatives of 3-(N-Naphthylaminocarbonyl)-2-propenoic Acid

In an effort to develop new organotin materials for investigation and biocidal evaluation, a series of compounds with the general formula R4−nSnLn (where R = CH3, n-C4H9, C6H5, C6H5CH2and L = 3-(N-naphthylaminocarbonyl)-2-propenoic acid) were synthesised, and characterised by elemental analysis, IR, multinuclear (1H, 13C and 119Sn) NMR, 119mSn Mössbauer spectroscopy and mass spectrometry. The biological activity of these compounds against various bacteria and fungi was investigated. All of the compounds were active against the fungi tested with a few exceptions. These compounds also showed significant antibacterial activity. LD50 data show that the investigated compounds have significant toxicity. Key Words: Organotin(IV) carboxylates, biological studies, spectroscopic studies