SUMMARY. Clearance of Escherichia coli in experimental cystitis was studied in the diuresing mouse model. Urine was collected daily; sediment was isolated by cytocentrifugation and either stained or treated with fluorescent antibodies directed against mouse immunoglo-bulins. During the initial phase of the infection the bacteria were either free and dispersed or adhering to epithelial cells but not generally to polymorphonuclear cells (PMNs). Subsequently, the bacteria adhered to each other, to epithelial cells and to PMNs, were phagocytosed by the latter and showed strong fluorescence. It is postulated that the appearance of opsonising and agglutinating antibodies in conjunction with activity of the PMNs is involved in bacterial clearance
<p>Colonization levels following independent infections of female CBA/J mice with (A) UPEC strain CF...
Various compromised host models were created in mice for use in pathological studies of urinary trac...
<p>Female C57Bl/6 mice were instilled with UTI89-RFP and bladders were processed for flow cytometry ...
Summary. Clearance of various bacteria isolated from portal and systemic blood of mice was evaluated...
ABSTRACT Infection with uropathogenic Escherichia coli (UPEC), the causative agent of most uncomplic...
This study examined the role of neutrophil leukocytes for the antibacterial defense at mucosal infec...
This study investigated the urinary tract cytokine reponse to infection and the role of chemokines f...
Urethral obstruction may be caused by prostatic hypertrophy, urethral stricture, or encrustation of ...
Urinary tract infections are generally preceded by transfer of organisms from the distal urethra to ...
<p>The bladder urothelium (A) is a pseudostratified transitional epithelium lined by large facet cel...
<p>(A) Experimental scheme used in the study. (B) Female C57Bl/6 (WT) or RAG2<sup>-/-</sup> mice wer...
<p>(A) WT mice underwent IM. Representative photomicrographs of bacterial internalization into the p...
<p>The E. coli isolate from a urine specimen positive for IBCs and filaments was inoculated into mic...
(A) In the inbred mouse strain C3H/HeN, inoculation with 108 CFU of the clinical UPEC isolate UTI89 ...
<p><i>E</i>. <i>coli</i> isolates MM242, MM243, MM244, MM248, and MM259, positive controls CFT073 an...
<p>Colonization levels following independent infections of female CBA/J mice with (A) UPEC strain CF...
Various compromised host models were created in mice for use in pathological studies of urinary trac...
<p>Female C57Bl/6 mice were instilled with UTI89-RFP and bladders were processed for flow cytometry ...
Summary. Clearance of various bacteria isolated from portal and systemic blood of mice was evaluated...
ABSTRACT Infection with uropathogenic Escherichia coli (UPEC), the causative agent of most uncomplic...
This study examined the role of neutrophil leukocytes for the antibacterial defense at mucosal infec...
This study investigated the urinary tract cytokine reponse to infection and the role of chemokines f...
Urethral obstruction may be caused by prostatic hypertrophy, urethral stricture, or encrustation of ...
Urinary tract infections are generally preceded by transfer of organisms from the distal urethra to ...
<p>The bladder urothelium (A) is a pseudostratified transitional epithelium lined by large facet cel...
<p>(A) Experimental scheme used in the study. (B) Female C57Bl/6 (WT) or RAG2<sup>-/-</sup> mice wer...
<p>(A) WT mice underwent IM. Representative photomicrographs of bacterial internalization into the p...
<p>The E. coli isolate from a urine specimen positive for IBCs and filaments was inoculated into mic...
(A) In the inbred mouse strain C3H/HeN, inoculation with 108 CFU of the clinical UPEC isolate UTI89 ...
<p><i>E</i>. <i>coli</i> isolates MM242, MM243, MM244, MM248, and MM259, positive controls CFT073 an...
<p>Colonization levels following independent infections of female CBA/J mice with (A) UPEC strain CF...
Various compromised host models were created in mice for use in pathological studies of urinary trac...
<p>Female C57Bl/6 mice were instilled with UTI89-RFP and bladders were processed for flow cytometry ...