BIOPHYSICAL, MEDICAL, ENVIRONMENTAL PHYSICS SOME OPTIMIZATIONS OF BIO-FETs WITH ELECTRICAL CHARGED BIOLIQUID

Abstract. The Bio-FETs are achieved with a matrix of receptor-analyte, coupled with an MOS Field Effect Transistor. The analytes could be antigens, proteins, hormons. The analytes binding provides a bias for the MOSFET transistor, but small enough. In this paper an optimisation is proposed of Bio-FETs that accumulate electric charge in the gate space, in order to increase the gate voltage with the same analyte concentration. This is possible by finding an optimum place for the receptor layer. Key words: Biosensors, Field Effects Transistors, sensitivity optimisations, analytical methods