Correspondence

BackgroundaaParaneoplastic neurological disorders associated with anti-Ri-antibodies, which are typically present with opsoclonus-myoclonus-ataxia. Most cases with anti-Ri-antibodyasso-ciated paraneoplastic syndrome due to breast cancer occur in women- its occurrence in men is extremely rare. Case ReportaaWe present herein the case of a male patient with breast cancer who had atypical anti-Ri-antibody-associated paraneoplastic syndrome presenting as complete horizontal ophth-almoplegia, left trigeminal sensory symptoms, and truncal ataxia. Following the diagnosis of paraneoplastic syndrome, chemotherapy and immunomodulating treatment including intrave-nous immunoglobulin and oral prednisolone were administered. Although the patient was ne-gative for serum anti-Ri-antibodies 14 weeks later, his symptoms persisted. ConclusionsaaTo our knowledge, this is the first case report of ophthalmoplegia without op-soclonus-myoclonus in a male anti-Ri-antibody-positive patient with breast cancer