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colo form ne 1 Angiogenesis plays a critical role in several pathological transport of inflammatory cells. Recently, we have shown that factor (PAF) by endothelial cells (EC) [3]. VEGF-mediated for VEGF-A165-mediated endothelial P-selectin translocation and neutrophil adhesion onto activated EC [3,6,7], essential events in the induction of acute inflammatory processes. Recently, a new class of angiogenic factors, angiopoietins Cellular Signalling 18 (2006conditions, namely atherosclerosis, proliferative retinopathies, and tumor growth [1]. Previous studies established the contribution of vascular endothelial growth factor (VEGF-A165) and the cell signalling mechanisms by which it leads to angiogenesis [1]. Namely, it has been reported that inflammatio