Influence of Geometric and Hemodynamic Parameters on Aneurysm Visualization during Three-Dimensional Rotational Angiography: An in Vitro Study

angiography is influenced by investigator-defined parameters such as image acquisition and contrast agent injection and by the hemodynamic pattern in the parent artery and aneurysm. To assess the impact of the geometric configuration of parent artery and aneurysm on the 3D visualization of saccular aneurysms, we studied silicone aneurysm models under pulsatile-flow conditions. METHODS: Rotational angiography was performed in three bifurcation and three lateral aneurysm models with ostia of different widths. Three acquisition modalities (5, 8, and 14 seconds in duration, acquisition rate of 10 frames per second) and two techniques for the injection of contrast material (continuous flow and injection with an initial bolus) were applied. 3D reconstructions were obtained with a volume-rendering technique. RESULTS: Bifurcation aneurysms were visualized with high accuracy. Filling deficits distant to the inflow zone could be compensated for with the bolus-injection technique, and complete depiction of aneurysm shape was achieved in the 8-second rotation with 20 mL of contrast agent. In lateral aneurysms, the accuracy of 3D reconstructions depended on the width of the ostium. Although rotational studies in wide-necked lateral aneurysms yielded adequate recon