Non-lesional localization-related epilepsy

Presurgical evaluation and the surgical treatment of non-lesional neocortical epilepsy is one of the most challenging areas in epilepsy practice. The resection of the epileptogenic lesion with the ictal onset zone is recognized as the most important factor for good surgical outcome. However, in the case of no structural lesion on MRI, the correct localization of the epileptogenic foci seems to be difficult. In addition to this problem, characteristics of neocortical epilepsy such as a widespread epileptogenic process, rapid propagation of the ictal rhythm, and the presence of eloquent areas also contribute to poor prognosis. We evaluated the surgical outcome and the diagnostic role of ictal scalp EEG, interictal FDG