Add to ORKGThis report describes an analysis of the red blood cell proteome by ion trap tandem mass spectrometry in line with liquid chromatography. Mature red blood cells lack all internal cell structures and consist of cytoplasm within a plasma membrane envelope. To maximize outcome, total red blood cell protein was divided into two fractions of membrane-associated proteins and cytoplasmic pro-teins. Both fractions were divided into subfractions, and proteins were identified in each fraction separately through tryptic digestion. Membrane protein digests were collected from externally exposed proteins, internally ex-posed proteins, “spectrin extract ” mainly consisting of membrane skeleton proteins, and membrane proteins mi-nus spectrin extract. Cyto...
Platelets are essential for maintaining vascular integrity. Given the anucleate nature of platelets,...
In-depth human erythrocyte proteome studies are severely hampered by the presence of hemoglobin and ...
Red blood cells (RBCs, erythrocytes) are the simplest primary human cells, lacking nuclei and major ...
The erythrocyte cytoplasmic proteome is composed of 98% hemoglobin; the remaining 2% is largely unex...
Red blood cells (RBCs) are the most abundant cell type in the human body. RBCs and, in particular, t...
Background Red blood cell (RBC) physiology is directly linked to many human disorders associated wit...
International audienceMass spectrometry-based proteomics now enables the absolute quantification of ...
Erythropoiesis is marked by progressive changes in morphological, biochemical and mechanical propert...
Since red blood cells (RBCs) lack nuclei and organelles, cell membrane is their main load-bearing co...
During the past decade, the hand-in-hand development of biotechnology and bioinformatics has enabled...
Based on recent results, the determination of the easily accessible red blood cell (RBC) membrane pr...
INSTITUTE The comprehensive analysis of the normal human red cell proteome reported by Pasini and co...
This thesis describes both the development and the implementation of novel strategies of mass spectr...
Improvements in proteome analysis of erythrocyte membrane proteins by two-dimensional electrophoresi...
Background. Several hereditary hemolytic anemias associated with the abnormal red cell shapes, such ...
Platelets are essential for maintaining vascular integrity. Given the anucleate nature of platelets,...
In-depth human erythrocyte proteome studies are severely hampered by the presence of hemoglobin and ...
Red blood cells (RBCs, erythrocytes) are the simplest primary human cells, lacking nuclei and major ...
The erythrocyte cytoplasmic proteome is composed of 98% hemoglobin; the remaining 2% is largely unex...
Red blood cells (RBCs) are the most abundant cell type in the human body. RBCs and, in particular, t...
Background Red blood cell (RBC) physiology is directly linked to many human disorders associated wit...
International audienceMass spectrometry-based proteomics now enables the absolute quantification of ...
Erythropoiesis is marked by progressive changes in morphological, biochemical and mechanical propert...
Since red blood cells (RBCs) lack nuclei and organelles, cell membrane is their main load-bearing co...
During the past decade, the hand-in-hand development of biotechnology and bioinformatics has enabled...
Based on recent results, the determination of the easily accessible red blood cell (RBC) membrane pr...
INSTITUTE The comprehensive analysis of the normal human red cell proteome reported by Pasini and co...
This thesis describes both the development and the implementation of novel strategies of mass spectr...
Improvements in proteome analysis of erythrocyte membrane proteins by two-dimensional electrophoresi...
Background. Several hereditary hemolytic anemias associated with the abnormal red cell shapes, such ...
Platelets are essential for maintaining vascular integrity. Given the anucleate nature of platelets,...
In-depth human erythrocyte proteome studies are severely hampered by the presence of hemoglobin and ...
Red blood cells (RBCs, erythrocytes) are the simplest primary human cells, lacking nuclei and major ...