blastoma resists conventional treat-ment; hence, novel therapeutic ap-proaches are required. We evaluated the use of c-myb antisense oligodeoxy-nucleotides (asODNs) delivered to cells via targeted immunoliposomes to in-hibit c-Myb protein expression and neuroblastoma cell proliferation in vitro. Methods: Phosphorothioate asODNs and control sequences were encapsulated in cationic lipid, and the resulting particles were coated with neutral lipids to produce coated cat-ionic liposomes (CCLs). Monoclonal antibodies directed against the disialo
AbstractThe development of long-circulating formulations of liposomes (S-liposomes), sterically stab...
Purpose: Sepantronium bromide (YM155) is a hydrophilic quaternary compound that cannot be administer...
We have developed a technology for efficiently enhancing the anticancer apoptosis-inducing activity ...
BACKGROUND:Advanced-stage neuroblastoma resists conventional treatment; hence, novel therapeutic app...
neuroblastoma, the most common extracranial solid tumor of infancy, is linked with cell proliferatio...
Since their discovery by Bangham about 50 years ago, liposomes have become promising tools in drug d...
AbstractAntisense gene therapy using molecules such as antisense oligodeoxynucleotides, siRNA or miR...
Cationic immunoliposomes were prepared by conjugation of Fab ' fragments of the recombinant hum...
Phosphorothioate c-myc antisense oligodeoxynucleotides [S]ODNs (free INX-6295) were encapsulated in ...
Nanoscale drug delivery systems, such as sterically stabilized immunoliposomes binding to internaliz...
Accessibility of tumors for highly effective local treatment represents a major challenge for antica...
In this thesis, a Trojan horse strategy with antibody-targeted liposomes has been followed to obtain...
AbstractThe selective toxicity of anticancer drugs can be improved with the use of antibody-targeted...
AbstractLigand-targeted liposomes have the potential to increase the therapeutic efficacy of antineo...
International audienceThis study proposes liposomes as a new tool for pretargeted radioimmunotherapy...
AbstractThe development of long-circulating formulations of liposomes (S-liposomes), sterically stab...
Purpose: Sepantronium bromide (YM155) is a hydrophilic quaternary compound that cannot be administer...
We have developed a technology for efficiently enhancing the anticancer apoptosis-inducing activity ...
BACKGROUND:Advanced-stage neuroblastoma resists conventional treatment; hence, novel therapeutic app...
neuroblastoma, the most common extracranial solid tumor of infancy, is linked with cell proliferatio...
Since their discovery by Bangham about 50 years ago, liposomes have become promising tools in drug d...
AbstractAntisense gene therapy using molecules such as antisense oligodeoxynucleotides, siRNA or miR...
Cationic immunoliposomes were prepared by conjugation of Fab ' fragments of the recombinant hum...
Phosphorothioate c-myc antisense oligodeoxynucleotides [S]ODNs (free INX-6295) were encapsulated in ...
Nanoscale drug delivery systems, such as sterically stabilized immunoliposomes binding to internaliz...
Accessibility of tumors for highly effective local treatment represents a major challenge for antica...
In this thesis, a Trojan horse strategy with antibody-targeted liposomes has been followed to obtain...
AbstractThe selective toxicity of anticancer drugs can be improved with the use of antibody-targeted...
AbstractLigand-targeted liposomes have the potential to increase the therapeutic efficacy of antineo...
International audienceThis study proposes liposomes as a new tool for pretargeted radioimmunotherapy...
AbstractThe development of long-circulating formulations of liposomes (S-liposomes), sterically stab...
Purpose: Sepantronium bromide (YM155) is a hydrophilic quaternary compound that cannot be administer...
We have developed a technology for efficiently enhancing the anticancer apoptosis-inducing activity ...