Add to ORKGcancer and are important in serum studies, for which glycosylation is a common posttranslational modifica-tion. Methods: We used multilectin affinity chromatography (M-LAC) to isolate glycoproteins from the sera of breast cancer patients and controls. The proteins were identi-fied by HPLC–tandem mass spectrometry (MS/MS) analysis of the corresponding tryptic digests. We used the FuncAssociate Gene Ontology program for associa-tion analysis of the identified proteins. Biomarker can-didates in these groups were comparatively quantitated by use of peak area measurements, with inclusion of an internal standard. We analyzed data for concordance within the ontology association groups for vector of change with the development of breast cancer
In this study, we report a plasma proteomic analysis of a mouse MCF7 xenograft, using a novel platfo...
Altered protein glycosylation compared to the disease-free state is a universal feature of cancer ce...
In order to discover potential glycoprotein biomarkers in ovarian cancer, we applied a lectin array ...
cancer and are important in serum studies, for which glycosylation is a common posttranslational mod...
Protein glycosylation represents one of the major post-translational modifications and can have sign...
The discovery of breast cancer associated plasma/serum biomarkers is important for early diagnosis, ...
The major objective of the work presented in this thesis was to develop a global targeted glycoprote...
Aberrations in protein glycosylation are a common phenotype in cancer. These cancer-associated glyca...
Glycoproteins in human serum play fundamental roles in many biological processes, and also have clin...
We used a lectin chromatography/MS-based approach to screen conditioned medium from a panel of lumin...
Liquid phase glycoprotein enrichment, fractionation and glycoprotein microarray techniques based on ...
Aberrant glycosylation on glycoproteins that are either presented on the surface or secreted by canc...
Because the glycosylation of proteins is known to change in tumor cells during the development of br...
Biomarker discovery can identify molecular markers in various cancers that can be used for detection...
Protein glycosylation fingerprints are widely recognized as potential markers for disease states, an...
In this study, we report a plasma proteomic analysis of a mouse MCF7 xenograft, using a novel platfo...
Altered protein glycosylation compared to the disease-free state is a universal feature of cancer ce...
In order to discover potential glycoprotein biomarkers in ovarian cancer, we applied a lectin array ...
cancer and are important in serum studies, for which glycosylation is a common posttranslational mod...
Protein glycosylation represents one of the major post-translational modifications and can have sign...
The discovery of breast cancer associated plasma/serum biomarkers is important for early diagnosis, ...
The major objective of the work presented in this thesis was to develop a global targeted glycoprote...
Aberrations in protein glycosylation are a common phenotype in cancer. These cancer-associated glyca...
Glycoproteins in human serum play fundamental roles in many biological processes, and also have clin...
We used a lectin chromatography/MS-based approach to screen conditioned medium from a panel of lumin...
Liquid phase glycoprotein enrichment, fractionation and glycoprotein microarray techniques based on ...
Aberrant glycosylation on glycoproteins that are either presented on the surface or secreted by canc...
Because the glycosylation of proteins is known to change in tumor cells during the development of br...
Biomarker discovery can identify molecular markers in various cancers that can be used for detection...
Protein glycosylation fingerprints are widely recognized as potential markers for disease states, an...
In this study, we report a plasma proteomic analysis of a mouse MCF7 xenograft, using a novel platfo...
Altered protein glycosylation compared to the disease-free state is a universal feature of cancer ce...
In order to discover potential glycoprotein biomarkers in ovarian cancer, we applied a lectin array ...