Add to ORKGSince the discovery of the CFTR gene in 1989, many efforts have been made to develop an efficacious and safe gene transfer system for gene therapy of Cystic Fibrosis (CF) directed to the airways. Here we review the most recent findings and development in nonviral and viral vectors used to transfer the CFTR cDNA into the airway epithelial cells of CF patients and animal models
Since the discovery of the CFTR gene, researchers have been working to develop a gene therapy techni...
AbstractGene delivery systems (GDS) play a central role in the development of gene therapy strategie...
A gene therapy for cystic fibrosis (CF) lung disease by intralumenal delivery of therapeutic transge...
Gene therapy has been proposed for a wide range of human diseases but few have received the level of...
Clinical trials in cystic fibrosis (CF) patients established proof-of-principle for transfer of the ...
AbstractClinical trials in cystic fibrosis (CF) patients established proof-of-principle for transfer...
Clinical trials in cystic fibrosis (CF) patients established proof-of-principle for transfer of the ...
AbstractGene delivery systems (GDS) play a central role in the development of gene therapy strategie...
Abstract The identification of the cystic fibrosis (CF) gene opened the way for gene therapy. In the...
Gene therapy is being developed as a novel treatment for cystic fibrosis (CF), a condition that has ...
Abstract: Cystic fibrosis (CF) is caused by mutations of the CF transmembrane conductance regulator ...
Gene therapy of cystic fibrosis (CF) lung disease needs highly efficient delivery and long-lasting c...
Gene therapy of cystic fibrosis (CF) lung disease needs highly efficient delivery and long-lasting c...
We use both large and small animal models in our pre-clinical evaluation of gene transfer agents (GT...
Abstract: Cystic fibrosis is a monogenic disorder with significant morbidity and mortality, despite ...
Since the discovery of the CFTR gene, researchers have been working to develop a gene therapy techni...
AbstractGene delivery systems (GDS) play a central role in the development of gene therapy strategie...
A gene therapy for cystic fibrosis (CF) lung disease by intralumenal delivery of therapeutic transge...
Gene therapy has been proposed for a wide range of human diseases but few have received the level of...
Clinical trials in cystic fibrosis (CF) patients established proof-of-principle for transfer of the ...
AbstractClinical trials in cystic fibrosis (CF) patients established proof-of-principle for transfer...
Clinical trials in cystic fibrosis (CF) patients established proof-of-principle for transfer of the ...
AbstractGene delivery systems (GDS) play a central role in the development of gene therapy strategie...
Abstract The identification of the cystic fibrosis (CF) gene opened the way for gene therapy. In the...
Gene therapy is being developed as a novel treatment for cystic fibrosis (CF), a condition that has ...
Abstract: Cystic fibrosis (CF) is caused by mutations of the CF transmembrane conductance regulator ...
Gene therapy of cystic fibrosis (CF) lung disease needs highly efficient delivery and long-lasting c...
Gene therapy of cystic fibrosis (CF) lung disease needs highly efficient delivery and long-lasting c...
We use both large and small animal models in our pre-clinical evaluation of gene transfer agents (GT...
Abstract: Cystic fibrosis is a monogenic disorder with significant morbidity and mortality, despite ...
Since the discovery of the CFTR gene, researchers have been working to develop a gene therapy techni...
AbstractGene delivery systems (GDS) play a central role in the development of gene therapy strategie...
A gene therapy for cystic fibrosis (CF) lung disease by intralumenal delivery of therapeutic transge...