Arq Neuropsiquiatr 1998;56(3-B):658-660 HEMORRHAGIC CEREBRAL METASTASIS AS A FIRST MANIFESTATION OF A HEPATOCELLULAR CARCINOMA

ABSTRACT- We report herein a rare instance in which a patient presented with a hemorrhagic cerebral metastasis as the initial manifestation of a hepatocellular carcinoma (HCC). A few cases of cerebral metastasis from HCC have been reported in the literature, mainly from eastern countries. This is the first report from South America of a cerebral metastasis from hepatocellular carcinoma. KEY WORDS: hepatocellular carcinoma, metastases, brain, hemorrhage. Metástase cerebral hemorrágica como manifestação inicial de um carcinoma hepatocelular: relato de caso RESUMO- Relatamos o caso de um paciente que teve como primeira manifestação de um carcinoma hepatocelular uma metástase cerebral hemorrágica, evento raro na literatura. Os poucos casos de metástase cerebral por carcinoma hepatocelular foram relatados em países do Oriente, onde o tumor é mais comum. Este é o primeiro relato de metástase cerebral de carcinoma hepatocelular da América do Sul. PALAVRAS-CHAVE: carcinoma hepatocelular, metástase cerebral, hemorragia. The epidemiology of hepatocellular carcinoma (HCC) in the world is according to geographic location. It is unusual in Western countries (incidence of 5/100.000) but commonner in Orient and Africa (20-150/100.000)1,2. Cerebral metastases are rare, in all regions, being a postmortem finding in the majority of cases