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chizophrenia is a severe psychiatric disorder that signifi-cantly impairs a person’s ability to think clearly, manage emotions, make decisions, and relate to others. Many bio-chemical theories attempt to explain the primary pathophysiological changes in schizophrenia. The DA hypothesis, which postulates hyperdopaminergia in the mesolimbic dopamine system and hypodopaminergia in the mesocortical dopamine system (1), is one of the most popular biochemical theories but is limited by its inability to account for all aspects of the illness. Other neurotransmitter systems that have been implicated and that are being examined for their role in schizophrenia include glutamate, serotonin, and GABA. NASs play a modulatory role in the central nervous system and affect many of these neurotransmitter systems. NASs have not been extensively studied in schizophrenia, ye