BMB reports

density lipoprotein, Reverse cholesterol transport Biomedicinal implications of high-density lipoprotein: its composition, structure, functions, and clinical applications Kyung-Hyun Cho* School of Biotechnology, Yeungnam University, Gyeongsan 712-749, Korea High-density lipoprotein (HDL) is a proven biomarker for the monitoring of changes in antioxidant and anti-inflammation capability of body fluids. The beneficial virtues of HDL are highly dependent on its lipids and protein compositions, and their ratios. In normal state, the HDL particle is enriched with lipids and several HDL-associated enzymes, which are respon-sible for its antioxidant activity. Lower HDL-cholesterol levels (＜40 mg/dL) have been recognized as an independent risk factor for coronary artery disease, as well as being a known component of metabolic syndrome. Functional and structura