Dedifferentiated Chondrosarcoma of the Larynx

Summary: A 74-year-old man with a history of a chondroid lesion of the larynx noted an enlarging neck mass. Axial CT showed a large expansile lesion arising from the left thyroid cartilage. Multiple rings and arcs with relatively intact cortex indicated a chondroid lesion. Irregularity of the anterolateral margin abutted a prominent soft-tissue component. The specimen obtained from fine needle aspi-ration was suggestive of a malignant fibrous histiocytoma. After further resection, the final diagnosis was dedifferen-tiated chondrosarcoma. A new soft-tissue component or rapid growth of the mass can be indicative of a diagnosis of dedifferentiated chondrosarcoma. Chondrosarcomas are rare tumors accounting for less than 1 % of all laryngeal tumors (1, 2). Unlike other head and neck chondrosarcomas, laryngea